Scientific reports

Sci Rep · ISSN (e) 2045-2322 · 885 papers in corpus
observational 2025
doi:10.1038/s41598-025-97243-5 ·PMID:40246879

Female infertility is a prevalent condition closely linked with obesity. Current evaluation metrics like body mass index (BMI) and waist circumference (WC) have limitations. Relative fat mass (RFM) is a newer, more accurate obesity metric, …

observational 2025
doi:10.1038/s41598-025-05152-4 ·PMID:40594282

This study aims to explore the association between stress coping and primary dysmenorrhea among Chinese female adolescent students. A two-step random, stratified, cluster sampling method was employed to assess the health status of female ad…

observational 2025
doi:10.1038/s41598-025-09161-1 ·PMID:40610595

The high rate of unexplained female infertility significantly affects public health and women's mental well-being. Research on dietary nutrients' impact on infertility often overlooks vitamin B2. Exploring this vitamin's role could be cruci…

observational 2025
doi:10.1038/s41598-025-23666-9 ·PMID:41238678

Accumulated evidence has shown that the antioxidant diet exhibits protective effects on women's reproductive health. The Composite Dietary Antioxidant Index (CDAI) serves as a crucial indicator for assessing antioxidant-rich diets. However,…

observational 2025
doi:10.1038/s41598-025-08595-x ·PMID:40595186

Relative Fat Mass (RFM) is an emerging body fat measurement index that more accurately reflects the distribution of visceral fat. This study aimed to investigate the association between RFM and female infertility. We utilized data from the …

diagnostic-accuracy 2025
doi:10.1038/s41598-025-14646-0 ·PMID:40855090

The incidence of urothelial carcinoma (UC) ranks second among all urological cancers, accounting for over 90% of malignant tumors in bladder. Patients diagnosed with UC experience a lower quality of life due to rapid progression of the dise…

lab-animal 2025
doi:10.1038/s41598-025-11594-7 ·PMID:40715274

BACKGROUND: Bone nonunion is a major complication in fracture treatment. Despite considerable advancements in fracture care, 5-10% of fractures result in nonunion; This demonstrates the requirement for novel molecules to enhance fracture he…

lab-animal 2025
doi:10.1038/s41598-025-31035-9 ·PMID:41339444

Bile reflux, resulting from pancreaticobiliary reflux (PBR), not only alters the chemical of bile but also constitutes a significant risk factor for the occurrence and development of gallbladder cancer. In previous studies, the authors iden…

other 2025
doi:10.1038/s41598-025-17347-w ·PMID:40851102

This study investigated the migration of bisphenol A (BPA) from polyethylene terephthalate (PET) bottles into Iranian yogurt drink (Doogh), under different storage conditions and assessed the associated health risks. Three doogh brands were…

observational 2025
doi:10.1038/s41598-025-20150-2 ·PMID:41107304

The relationship between blastocyst morphological quality and the risk of congenital malformations in assisted reproductive technology (ART) remains poorly understood, limiting clinical decision-making for embryo selection. We conducted a r…

other 2025
doi:10.1038/s41598-025-87415-8 ·PMID:39863658

Menstrual pain affects women's quality of life and productivity, yet objective molecular markers for its severity have not been established owing to the variability in blood levels and chemical properties of potential markers such as plasma…

lab-animal 2025
doi:10.1038/s41598-025-13900-9 ·PMID:40781536

Endometriosis (ENDO), a chronic inflammatory disease affecting approximately 190 million women globally, is characterized by fibrosis, a feature often challenging to replicate in murine models. To identify an optimal syngeneic model exhibit…

other 2025
doi:10.1038/s41598-025-86707-3 ·PMID:39837933

Dietary factors have recently been recognized as potentially influential in the pathogenesis of endometriosis (EM), yet studies on the causal relationship between dietary preferences and EM are limited. The present study aimed to explore th…

other 2025
doi:10.1038/s41598-025-26412-3 ·PMID:41309741

To evaluate the synergistic predictive capacity of MRI lesion classification and serum CA125 for symptom manifestation (dysmenorrhea/menorrhagia) and explore associated adenomyosis pathogenesis. Patients before focused ultrasound ablation s…

rct 2025
doi:10.1038/s41598-025-32974-z ·PMID:41476263

Symptomatic adenomyosis is a known impediment to successful implantation and pregnancy in in vitro fertilization; yet optimal pre-treatment strategic approach remains uncertain. This randomized controlled trial compared the effects of low d…

other 2025
doi:10.1038/s41598-025-02689-2 ·PMID:40419615

Poor ovarian response (POR) is a challenge in reproductive medicine, often leading to suboptimal outcomes in IVF/ICSI cycles. Autologous platelet-rich plasma (PRP) injections have emerged as a potential therapy to enhance ovarian function. …

meta-analysis 2025
doi:10.1038/s41598-025-93705-y ·PMID:40102483

The debate around colorectal surgery for endometriosis has been ongoing, but to date no meta-analysis has investigated the impact of the different surgical approaches on the pregnancy rate. The aim of this meta-analysis study was to determi…

other 2025
doi:10.1038/s41598-025-19216-y ·PMID:41068242

This prospective study evaluated ChatGPT-4 as a decision-support tool by comparing its treatment recommendations with clinical decisions for 87 women (aged 40-65 years) scheduled for hysterectomy. Demographic, clinical, and ultrasonographic…

observational 2025
doi:10.1038/s41598-025-16525-0 ·PMID:40836001

This study compared the surgical outcomes of total laparoscopic hysterectomy (TLH) and vaginal-assisted natural orifice transluminal endoscopic surgery (vNOTES) in patients with a history of gynecologic and obstetric surgery. This cross-sec…

other 2025
doi:10.1038/s41598-025-92906-9 ·PMID:40065148

Chronic endometritis (CE) and endometrial dysbiosis (ED) are major causes of recurrent implantation failure (RIF). CE is diagnosed via hysteroscopy or the endometrial CD138 test; ED is examined using endometrial microbiome testing with next…

other 2025
doi:10.1038/s41598-024-83575-1 ·PMID:39799203

This is the first study to evaluate the adequacy and reliability of the ChatGPT and Gemini chatbots on viral hepatitis. A total of 176 questions were composed from three different categories. The first group includes "questions and answers …

nonrandomized-trial 2025
doi:10.1038/s41598-025-99468-w ·PMID:40287476

Therapeutics for thin endometrium (TE) have emerged, with autologous platelet-rich plasma (PRP) therapy gaining significant attention. In the present study, ten eligible TE patients were recruited for PRP infusion. Endometrial tissue biopsi…

other 2025
doi:10.1038/s41598-025-89371-9 ·PMID:39962102

Existing models of health literacy have included a limited perspective of children and adolescents. We conducted a meta-ethnography to develop a child- and adolescent-centered conceptualization of health literacy. We dually screened 3564 ab…

lab-animal 2025
doi:10.1038/s41598-025-90329-0 ·PMID:39994247

Endometriosis is a refractory estrogen-dependent gynecological disease in which ovarian endometriosis(OE) is the most common, and the main cell components are endometrial epithelial cells and stromal cells. However, constructing ectopic end…

observational 2025
doi:10.1038/s41598-024-85017-4 ·PMID:39910174

Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissues (glands and stroma) located outside the uterine cavity. The pathophysiology of this condition remains incompletely understood. Local b…