The relationship between ovarian cysts and infertility is a subject of debate, mainly because it is difficult to determine the real impact of the cyst and its treatment on later fertility. For a long time it was hoped that surgical treatmen…
OBJECTIVE: To study the effects of two resolvins of D series, RvD1 and 17(R)-RvD1, on inflammatory signs associated with endometriosis (ENDO). DESIGN: In vivo research study. SETTING: Research laboratory. ANIMAL(S): Female Sprague-Dawley…
To determine the interest of using robotic laparoscopic surgery in the management of female infertility, we reviewed our own activity and searched the Medline database for publications on robotic technology in infertility surgery, with the …
OBJECTIVE: To investigate the amount of perceived stress in a group of women with different forms of endometriosis-related pain before and after surgical treatment. DESIGN: Prospective clinical trial. SETTING: University hospital. PATIEN…
OBJECTIVE: To investigate the balance between regulatory T cells (Treg) and T-helper 17 cells (T(H)17) in peripheral blood and uteri of women with adenomyosis (AM), and to evaluate their potential correlation with dysmenorrhea and CA-125 le…
OBJECTIVE: To evaluate the effects of laparoscopic cystectomy on ovarian reserve in patients with endometriomas. DESIGN: Prospective study. SETTING: Private and university hospitals. PATIENT(S): A total of 193 patients with endometriomas…
OBJECTIVE: To estimate the influence of prior oral contraceptive pill (OCP) use on future diagnosis of endometriosis in young women. DESIGN: Prospective cohort study, the Australian Longitudinal Study on Women's Health. SETTING: Community…
OBJECTIVE: To analyze the WNT/β-catenin signaling pathway in luteinized granulosa cells from women with and without endometriosis in relation to cellular apoptosis. DESIGN: Basic. SETTING: University hospital. PATIENT(S): Patients with a…
Pain associated with endometriosis may involve many mechanisms and requires careful evaluation to confirm the diagnosis and exclude other potential causes. Both medical and surgical treatments for pain related to endometriosis are effective…
OBJECTIVE: To prospectively examine whether the association between tubal ligation, hysterectomy, unilateral oophorectomy, and ovarian cancer varied by patient, tumor, and surgical characteristics. DESIGN: Two prospective cohort studies (N…
OBJECTIVE: To assess the accuracy of transvaginal sonography (TVS) in defining size and location of deep infiltrating endometriosis (DIE) with laparoscopic/histologic confirmation. DESIGN: Prospective observational study. SETTING: Univers…
OBJECTIVE: To evaluate the use of fertility treatments among a large cohort of women in the United States. DESIGN: Cohort study. SETTING: Nurses' Health Study II. PATIENT(S): Ten thousand thirty-six women who reported having used fertili…
OBJECTIVE: To model morphological assessments of embryo quality that are predictive of live birth. DESIGN: Longitudinal cohort using cycles reported in the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System (SART…
OBJECTIVE: To review systematically the literature on uterus-sparing surgical treatment options for adenomyosis. DESIGN: Systematic literature review. SETTING: Tertiary academic center. PATIENT(S): Women with histologically proven adenom…
OBJECTIVE: To assess the variability of follicular fluid (FF) high-density lipoprotein (HDL) particle components. DESIGN: Cross-sectional design with assessment using two-stage nested analysis of variance. SETTING: Reproductive health cen…
OBJECTIVE: To determine whether day 3 FSH and E2 levels at the upper limits of normal affect live-birth rates and treatment trajectory in a conventional versus "fast track" treatment program for IVF. DESIGN: Secondary analysis of two rando…
OBJECTIVE: To analyze the determinants of successful pregnancy following laparoscopic adenomyomectomy. DESIGN: Retrospective cohort study. SETTING: A general hospital. PATIENT(S): A total of 102 women who had a desire for pregnancy under…
OBJECTIVE: To standardize the recording of surgical phenotypic information on endometriosis and related sample collections obtained at laparoscopy, allowing large-scale collaborative research into the condition. DESIGN: An international co…
OBJECTIVE: To harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of human tissues relevant to endometriosis. DESIGN: An international collaboration involv…
OBJECTIVE: To harmonize the collection of nonsurgical clinical and epidemiologic data relevant to endometriosis research, allowing large-scale collaboration. DESIGN: An international collaboration involving 34 clinical/academic centers and…
OBJECTIVE: To harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of fluid biospecimens relevant to endometriosis. DESIGN: An international collaboration i…
OBJECTIVE: To investigate differences in the activity of matrix metalloproteinases (MMPs) 2 and 9 and their respective tissue inhibitors (TIMPs) in follicular fluid of women with endometriosis, to correlate the findings with IVF outcome, an…