Zentralblatt für Gynäkologie

The effects of the progestational compound dienogest (17 alpha-cyanomethyl-17 beta-hydroxy-estra-4,9-dien-3-one) on liver metabolism have been studied in 101 otherwise healthy women with endoscopically proven endometriosis. The women aged 1…

Endometriosis in an important disease especially for girls and young women. It often causes chronic complaints and infertility, requiring an early endoscopic diagnosis for their prophylaxis and therapy. The characteristics of endometriosis,…

Buserelin has been applied intranasal in 31 women of the reproductive age for endometriosis that had been diagnosed by laparoscopic and bioptic means. The treatment period was 6 month and hormonal changes were evaluated after 2, 4, 8, 12, 1…

Concentration of cytosolic progesterone receptor (PR) was measured by means of an exchange procedure in the endometria of 80 women. Investigations carried out in 35 normal menstruating females showed a gradual increase of PR during the preo…

We have treated 31 patients for 6 months at the UFK Tübingen. The AFS-score declined from 7.3 to 3.6, and the--for adhesions corrected--implantation-score from 3.5 to 0.5. Last decline was statistically significant. The endometriosis-specif…

In a survey it is reported on the antiprogestins mifepristone (RU 486) and gestrinone (R 2323). Thanks to its high reversible affinity for progesterone receptor mifepristone stops progesterone activity at its target organs. Mifepristone als…

The increasing incidence of endometrial cancer requires more attention to early detection. Postmenopausal women without symptoms were examined by progesterone challenge test (96 diabetics, 111 without diabetes) and by sonography (44 diabeti…

Basal body temperature of 168 cycles have been measured in 20 infertile women (age 21-31 years) with endometriosis. There were 10.1% anovulatory cycles, and in 22.5% of the 151 biphasic cycles the hyperthermic phase lasted less than 11 days…

Extragenitally localized endometriosis with necessity of treatment is very rare. By means of case reports topical problems of symptomatology, diagnostics and therapy of endometriosis intestini have been discussed from surgical point of view…

Authors report on a case of generalized endometriosis. A 29 years old patient suffered from a primary amenorrhea by reason of an aplastic uterine cervix and an incomplete vaginal aplasia. Endometriosis has been ascertainable histologically …

The pharmacology and the application in oral hormonal contraceptives of four new progestogens--gestodene, desogestrel, norgestimate, and dienogest--are described in a survey. Although derived from 19-norethisterone these progestogens exhibi…

42 patients with advanced epithelial ovarian carcinoma who were clinically free of disease after completed postoperative chemotherapy were submitted to second-look laparotomy at the University clinics of Bilbao and Santander, in Northern Sp…

A report given about a case of stromatosis uteri. The age of the patient was 42 years. This illness can be interpreted as a favourable form of sarcoma uteri. An intensive follow up is necessary following operative therapy.

30 patients who had been hysterectomized at the Kiel University Clinic of Obstetrics and Gynecology, and 83 patients who had undergone tubal sterilization by monopolar high frequency current or by endocoagulation according to Semm, were inv…

Endometriosis is one of the most frequent diseases in connection with female sterility, 3.2 per cent endometriosis was diagnosed in all operative cases from 1964 to 1984 but in all cases of sterility there were 10.8 per cent. Essentially th…

Since 1973 laser technology has found its way into gynecology as well as other branches of medicine. CO2-, Neodym-YAG-, and argon-laser have been used. Experience has been made with the laser treatment of benign and precancerous lesions of …

Fifty eight fertile female volunteers between 20 to 45 years were enrolled in a clinical trial to evaluate the efficacy and tolerance of the progestin dienogest (17 alpha-cyanomethyl-17 beta-hydroxyestra-4,9-dien-3-one, VEB Jenapharm Jena G…

Dienogest (17 alpha-cyanomethyl-17 beta-hydroxy-estra-4,9-dien-3-one, VEB Jenapharm, Jena, GDR), an orally active 19-nortestosterone derivative, was used firstly in the treatment of endometriosis. 57 patients (age 17-45 years) have been ent…

The implantation of section of cornual endometrium into ovaries of guinea pigs was carried out. The purpose of the work is to evaluate the dynamics of morphologic changes occurring in ovaries following implantation of endometrium. During a …

The effect of danazol in a dose of 400 mg-800 mg per day for 6 month was studied in 10 women and also chlormadinone acetate 2 X 2 mg per day. Clinical investigation and laboratory test were done before the therapy has been started, during t…

The authors supply a survey about the aetiology varied classification systems and the hormontherapy of endometriosis. We have described the advantages and disadvantages of the therapy with progestagens, danazol, gestrinon and Gn RH agonists…

Laparoscopy was performed in 24 girls, aged 12-16 with congenital colpatresia. Rokitansky-Küster-Hauser syndrome was diagnosed. In all girls, in addition to morphologically and functionally normal ovaries, lying highly on the lateral wall o…

We examined 70 cases of curettage (24 in normal proliferative phase and 46 with endometrial hyperplasia) and determined the percentage of clear cells among all glandular cells. The number of clear cells was increased in endometrium with hyp…

Complex investigations were performed for the evaluation of the local biological effect of the total cryodestruction of endometrium in 7 perimenopausal women with relapsing hyperplasia of the endometrium before and after (in 3-4.5 months) s…

This case report deals with a primary endometrioid carcinoma within a Morgagni hydatid in a 43 years old woman. The woman died 27 month after first operation. Morgagni hydatids should be exstirpated in any case with histologic examination f…