[Hormonal changes in buserelin therapy]
Non-randomised trial
OA: closed
CC0
AI-generated summary
Intranasal buserelin therapy in 31 women with laparoscopically diagnosed endometriosis induced significant hormonal changes, including decreased FSH, LH, progesterone, and estradiol levels over a six-month treatment period.
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Abstract
Buserelin has been applied intranasal in 31 women of the reproductive age for endometriosis that had been diagnosed by laparoscopic and bioptic means. The treatment period was 6 month and hormonal changes were evaluated after 2, 4, 8, 12, 17, 20, and 24 weeks. After 2 weeks we observed a decrease of FSH to the lower normogonadotropic range, and of progesteron to less than 0.5 ng/ml. After 4 weeks LH decreased to the lower normogonadotropic range and E2 was below 55 pg/ml. Prolactin concentrations varied between 6 and 8 ng/ml.
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Source provenance
- europepmc
- last seen: 2026-10-09T06:09:53.026058+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-10-08T21:14:10.100512+00:00
License: CC0
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