[The therapeutic value of second-look laparotomy in advanced ovarian carcinoma]

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Abstract

42 patients with advanced epithelial ovarian carcinoma who were clinically free of disease after completed postoperative chemotherapy were submitted to second-look laparotomy at the University clinics of Bilbao and Santander, in Northern Spain, between 1980 and 1987. Tumor was demonstrated in 22 of the cases (52.3%). This paper deals with the question of whether this knowledge and the ensuing change in therapy resulted in a longterm benefit for the patients or not. In our experience, this was not the case. All second-look-positive patients either died during the follow-up period, or showed tumor progression if they survived more than 6 months. Survival sank to 50% after only 24 months, and steadily thereafter to 0% after 78 months. The therapeutical value of second-look laparotomy is heavily questioned by these results.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Cystadenocarcinoma Endometriosis Neoplasm Recurrence, Local Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols Cystadenocarcinoma Cystadenocarcinoma Cystadenocarcinoma Endometriosis Endometriosis Endometriosis Female Follow-Up Studies Humans Neoplasm Recurrence, Local

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europepmc
last seen: 2026-08-05T06:13:34.187606+00:00
pubmed
last seen: 2026-05-13T22:09:25.758913+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine