[The therapeutic value of second-look laparotomy in advanced ovarian carcinoma]
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Second-look laparotomy in 42 patients with advanced ovarian carcinoma failed to demonstrate long-term survival benefits, as all identified tumor recurrences resulted in disease progression or death.
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Abstract
42 patients with advanced epithelial ovarian carcinoma who were clinically free of disease after completed postoperative chemotherapy were submitted to second-look laparotomy at the University clinics of Bilbao and Santander, in Northern Spain, between 1980 and 1987. Tumor was demonstrated in 22 of the cases (52.3%). This paper deals with the question of whether this knowledge and the ensuing change in therapy resulted in a longterm benefit for the patients or not. In our experience, this was not the case. All second-look-positive patients either died during the follow-up period, or showed tumor progression if they survived more than 6 months. Survival sank to 50% after only 24 months, and steadily thereafter to 0% after 78 months. The therapeutical value of second-look laparotomy is heavily questioned by these results.
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- europepmc
- last seen: 2026-09-20T09:27:46.357103+00:00
- pubmed
- last seen: 2026-05-13T22:09:25.758913+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine