The Journal of international medical research

This study was designed to investigate the levels of expression of steroidogenic factor 1 (SF-1) and steroidogenic acute regulatory protein (StAR) in endometriosis, and to explore the association between these two factors and the menstrual …

Introduction Danol (danazoI) is a synthetic steroid which has been found to be effective in the treatment of a variety of gynaecological and endocrinological disorders including endometriosis (Young & Blackmore 1977), fibroadenosis (Mansel …

Introduction The premenstrual syndrome (PMS) is a common condition in which a cluster of psychological and/or physical symptoms recur in the post-ovulatory phase of the cycle, subsiding with the onset of menstruation and not usually re-appe…

In conclusion, we find that danazol has proved to be highly effective as a treatment for endometriosis. On the dosage used, we have not achieved the freedom from side-effects which we had hoped for, but in general these have been much less …

We have established that danazol is an orally active pituitary gonadotrophin inhibitory agent devoid of oestrogenic and progestational activity. This steroid has weak, impeded androgenic activity. Danazol is unique in possessing such a prof…

A prospective randomized study was undertaken comparing the effectiveness of danazol with Enavid treatment of endometriosis. 5 patients were treated with Enavid (5 mg twice daily) and 11 with danazol (100 mg twice daily) the doses increased…

The effects of danazol an antiogonadotropin derivative of ethisterone on the pituitary and ovarian function in the rhesus monkey were determined. Monkeys were administered danazol (30 mg/kg) from either Days 1-9 (Group 1 4 monkeys) 3-20 (Gr…