British journal of cancer

Br J Cancer · ISSN (print) 0007-0920 · 130 papers in corpus
lab-animal 1992
doi:10.1038/bjc.1992.175 ·PMID:1616853

Aminolaevulinic acid (ALA) is the first committed step in haem synthesis. In the presence of excess ALA the natural regulatory feedback system is disrupted allowing accumulation of protoporphyrin IX (PP IX) the last intermediate product bef…

other 1991
doi:10.1038/bjc.1991.288 ·PMID:1892754

Murine monoclonal antibody CF511, raised against human ovarian clear cell carcinoma, detects a glycoprotein (Mr 600 kDa) called CF511 antigen which is elevated in the serum of many patients with ovarian carcinoma. A competitive enzyme-linke…

rct 1990
doi:10.1038/bjc.1990.388 ·PMID:2123115

Twelve premenopausal patients with advanced breast cancer were randomised to receive 3.75 or 7.5 mg of a slow release formulation of the luteinising hormone releasing hormone agonist leuprorelin once every 4 weeks. All patients were oestrog…

other 1990
doi:10.1038/bjc.1990.222 ·PMID:2390478

A detailed study was performed in 14 patients with epithelial ovarian tumours using the satellite probes 33.15, 228S and 216S to investigate the nature of somatic changes and frequency with which clonal changes could be demonstrated during …

observational 1990
doi:10.1038/bjc.1990.355 ·PMID:2223590

The serum CA125 level was determined by a one-step immunoradiometric assay method in patients with lung cancer. Increased serum CA125 levels were observed in 37.8% of patients with squamous cell cancer, in 30.0% of those with adenocarcinoma…

1990
doi:10.1038/bjc.1990.248 ·PMID:2167724

Serum levels of TAG 72 were measured in 726 serum samples from patients with benign and malignant gynaecological conditions in order to evaluate the clinical usefulness of TAG 72 alone or in combination with other tumour markers. Sixty-six …

other 1989
doi:10.1038/bjc.1989.397 ·PMID:2605105

The murine monoclonal antibody (Mab) against human common epithelial ovarian carcinoma, CF511, was generated by immunising mice with human fetal tissue extract from early first trimester, followed by booster injection of an ovarian cancer c…

other 1989
doi:10.1038/bjc.1989.360 ·PMID:2803956

We studied the effect of ovarian cancer and its chemotherapy on the urinary excretion of prostacyclin (PGI2) and thromboxane A2 (TxA2) hydration and metabolic products. In six patients we measured 6-keto-PGF1 alpha and 2,3-dinor-6-keto-PGF1…

other 1988
doi:10.1038/bjc.1988.250 ·PMID:3207605
diagnostic-accuracy 1988
doi:10.1038/bjc.1988.67 ·PMID:3162682

Tumour-associated trypsin inhibitor (TATI) is a 6 kD peptide isolated from the urine of a patient with ovarian cancer. Increased urinary excretion of TATI has earlier been observed in patients with gynaecological malignancies. The value of …

other 1987
doi:10.1038/bjc.1987.181 ·PMID:3663471
other 1986
doi:10.1038/bjc.1986.181 ·PMID:3017398
other 1986
doi:10.1038/bjc.1986.165 ·PMID:3730253
1986
other 1985
doi:10.1038/bjc.1985.175 ·PMID:2411281

Two assay procedures, an inhibition radioimmunoassay (Inhibition-RIA) and an immunoradiometric assay (IRMA), were established for the detection of circulating tumour-associated Ca antigen. There was a good correlation between results (r = 0…

other 1983
doi:10.1038/bjc.1983.129 ·PMID:6860546

Serum prolactin concentrations were measured in 135 postmenopausal patients with advanced breast cancer prior to their treatment with one of 3 endocrine therapies: aminoglutethimide (AG), tamoxifen (T) + AG, or T + AG + danazol. The mean le…

observational 1983
doi:10.1038/bjc.1983.127 ·PMID:6860544

A case-control study was conducted in Los Angeles County, California, of 127 endometrial cancer cases aged 45 years or less at diagnosis, to investigate the role of fertility, obesity and exogenous oestrogens in the development of the disea…

observational 1981
doi:10.1038/bjc.1981.121 ·PMID:7248160

Follicular-phase (Day 11) plasma prolactin, and plasma and urinary oestrogen levels of 70 nulliparous nuns were compared with those of 80 of their sisters, of whom 62 were parous. The nuns and their nulliparous sisters did not differ signif…

other 1970
doi:10.1038/bjc.1970.31 ·PMID:5451569

The effect of the progestogen medroxyprogesterone acetate on metastases from renal, endometrial and other tumours has been studied in 25 patients. Seven patients with renal and endometrial tumours had a useful response, pulmonary metastases…

other 1967
doi:10.1038/bjc.1967.15 ·PMID:6024507
other 1966
doi:10.1038/bjc.1966.8 ·PMID:5936686
other 1966
doi:10.1038/bjc.1966.39 ·PMID:5944274
other 1964
doi:10.1038/bjc.1964.49 ·PMID:14219535
review 1964
doi:10.1038/bjc.1964.23 ·PMID:14189674
other 1962
doi:10.1038/bjc.1962.24 ·PMID:14452177