The use of progestogen in the treatment of metastatic carcinoma of the kidney and uterine body

C H Paine, Paine CH, F W Wright, Wright FW, Ellis F, F Ellis
British journal of cancer · 1970 · vol. 24(2) , pp. 277–82 · doi:10.1038/bjc.1970.31 · PMID:5451569 · PMC2008579
Other OA: gold publisher-OA-unknown
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Medroxyprogesterone acetate induced useful responses in pulmonary metastases from renal and endometrial tumors within three months, while bony metastases remained unaffected.

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Abstract

The effect of the progestogen medroxyprogesterone acetate on metastases from renal, endometrial and other tumours has been studied in 25 patients. Seven patients with renal and endometrial tumours had a useful response, pulmonary metastases and a large primary renal tumour showing the greatest effect. Bony metastases were unaffected by the drug and were treated by local radiotherapy. If a response occurred, it did so within 3 months.

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MeSH descriptors

Kidney Neoplasms Medroxyprogesterone Neoplasm Metastasis Uterine Neoplasms Adenocarcinoma Adenocarcinoma Aged Bone Neoplasms Bone Neoplasms Bone Neoplasms Female Humans Kidney Neoplasms Lung Neoplasms Lung Neoplasms Male Medroxyprogesterone Middle Aged Neoplasm Metastasis Uterine Neoplasms

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