Frontiers in medicine

OBJECTIVES: This study aims to evaluate the safety and efficacy of ovarian vein embolization combined with polidocanol sclerotherapy for Venous-origin chronic pelvic pain (VO-CPP) and to elucidate potential risk factors affecting prognosis.…

INTRODUCTION: Hysteroscopic LNG-IUD suture fixation is an innovative procedure for treating adenomyosis, effectively addressing the issue of expulsion. However, this case report presents a failed outcome and offers an exploratory summary of…

Curcumin, a bioactive polyphenol derived from turmeric (Curcuma longa), has garnered substantial attention for its potent anti-inflammatory, antioxidant, and antineoplastic properties. This review explores the therapeutic potential of curcu…

BACKGROUND: Astute observers of health systems are aware that worldwide there is a clinical trend toward integrative and personalized models. Ayurveda, inherently by its theory and practice, a personalized system of healthcare. Evidence fro…

OBJECTIVE: Dysmenorrhea is a prevalent gynecological disorder impairing quality of life for women of reproductive age. Although traditional herbal decoctions (THDs) are widely used for dysmenorrhea in Korea, robust real-world evidence regar…

Endometriosis is a common gynecological disorder that requires accurate detection of ectopic lesions in laparoscopic images for effective diagnosis and treatment. However, existing deep learning-based detection methods face significant chal…

OBJECTIVE: To evaluate the association of high-intensity focused ultrasound (HIFU) combined with syndrome differentiation-based individualized traditional Chinese medicine (TCM) herbal therapy with 12-month clinical outcomes compared with H…

BACKGROUND: Endometriosis is associated with infertility, adverse assisted reproductive outcomes, and a high prevalence of intrauterine pathologies. Lesions such as endometrial polyps and chronic endometritis may impair endometrial receptiv…

BACKGROUND/OBJECTIVES: Intestinal endometriosis (IE) often presents with dyschezia, gastrointestinal (GI) dysfunction, dyspareunia, and dysmenorrhea. The impact of lesion localization and size on the severity of symptoms remains insufficien…

ObjectiveTo evaluate the impact of adjunctive levonorgestrel-releasing intrauterine device (LNG-IUD) placement on amenorrhea rates and hysterectomy risk following endometrial resection or ablation in women with abnormal uterine bleeding (AU…

IntroductionFrozen shoulder (FS) is a chronic and painful joint disorder characterized by progressive stiffness and functional limitation. Its multifactorial pathophysiology remains poorly understood, although emerging evidence suggests a r…

OBJECTIVE: This study aimed to explore the diagnosis and treatment of patients who have reached menarche but present with clinical manifestations of genital tract obstruction. METHODS: A retrospective analysis was conducted on 72 patients …

Endometriosis is an estrogen-dependent chronic inflammatory disorder in which ectopic endometrial-like tissue undergoes repeated injury, incomplete resolution, and progressive remodeling. Fibrosis is therefore not merely a terminal scar but…

INTRODUCTION: Acute respiratory distress syndrome (ARDS) manifests as acute pulmonary inflammation associated with high mortality. While intermittent prone positioning for 12-16 h is an essential intervention in managing severe ARDS, clinic…

BACKGROUND: Ovarian endometrioma (OEM) is a common manifestation of endometriosis and is associated with both local lesions and systemic alterations. While immune dysregulation and metabolic disturbances have been individually reported in e…

OHVIRA syndrome is a rare Müllerian duct anomaly characterized by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. Although typically diagnosed in adolescence, it can rarely present later in life. We present the case…

BACKGROUND: Primary dysmenorrhea (PD) is a common gynecological condition affecting a substantial proportion of women of reproductive age. Non-steroidal anti-inflammatory drugs often provide incomplete pain relief and may be associated with…

BACKGROUND: The clinical management of adenomyosis remains challenging. Pharmacological therapies and surgical approaches for adenomyosis have shown benefits but present important limitations, such as side effects, recurrence, and loss of f…

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often resulting in pain and infertility and affecting overall quality of life. Despite its prevalence, diagnostic delays p…

Adenomyosis (AM) is a common gynecological disorder with high prevalence among women of childbearing age. Although hysterectomy is the definitive treatment, it is considered unsuitable for patients who wish to preserve fertility, creating a…

Primary Ovarian Insufficiency, a condition characterized by early loss of ovarian function, illustrates the consequences of failing to act on menstrual cycle changes as early clinical signals. Menstrual disturbance is often the first presen…

Gynecologic disorders, including infections, sterile inflammatory diseases, endocrine abnormalities, and malignancies, share a common signature of dysregulated immunity within a uniquely hormone-responsive reproductive tract. Neutrophil ext…

BACKGROUND: Several biomarkers have been studied to explore the possibility of a non-invasive diagnosis of endometriosis. The aim of this review is to explore the possible role of the neutrophil-to-lymphocyte ratio (NLR) as a biomarker in t…

BACKGROUND: Ovarian torsion is a gynecologic emergency requiring timely management to preserve ovarian function and future fertility. Clinical presentation is heterogeneous and frequently non-specific, making the decision between operative …

BACKGROUND: Ovarian mucinous tumors are histologically classified into benign, borderline, and malignant categories, with borderline tumors generally demonstrating an intermediate prognosis. However, ovarian borderline mucinous tumors with …