Frontiers in medicine

BACKGROUND: Uterine mesonephric-like adenocarcinoma (MLA) is a rare and biologically aggressive subtype of endometrial carcinoma, estrogen receptor (ER) and progesterone receptor (PR) are typically absent or exhibit very low expression in t…

Tuberous sclerosis complex-associated lymphangioleiomyomatosis (TSC-LAM) is a rare systemic disorder characterized by smooth muscle-like cell proliferation, leading to cystic lung destruction, predominantly affecting women of reproductive a…

BACKGROUND: Herlyn-Werner-Wunderlich syndrome (HWWS) management typically requires hymenotomy. We describe the fully endoscopic, hymen-sparing septotomy in a patient with no history of sexual intercourse. CASE PRESENTATION: A 20-year-old p…

OBJECTIVE: To summarize the clinical features, risk factors, and maternal and fetal outcomes of spontaneous complete uterine rupture during the second and third trimester of pregnancy, and to explore key aspects of early identification and …

Mesothelioma cysts are benign tumor-like lesions derived from mesothelial cells. They mainly affect the peritoneum of the pelvic and abdominal cavities, and are more commonly found in the mesentery and greater omentum, while they are less l…

Infertility is a global public health issue, and a favorable endometrial environment is essential for successful assisted reproductive treatment. Endometrial polyps (EM) and hydrosalpinx (HD) are common gynecological disorders impairing the…

OBJECTIVE: Uterine angioleiomyoma (ALM) is a rare benign mesenchymal tumor. Its clinical management poses challenges due to difficulties in preoperative diagnosis, an increased risk of intraoperative bleeding due to its highly vascular natu…

PURPOSE: This study aimed to summarize the clinical characteristics, surgical management, and follow-up outcomes of patients with severe renal impairment caused by ureteral endometriosis. METHODS: We conducted a retrospective analysis of t…

BACKGROUND AND OBJECTIVE: Diagnosis and treatment strategies for adenomyosis are influenced by multiple factors, including patient preferences, adenomyosis subtype, and disease progression, with no standardized protocol currently establishe…

OBJECTIVE: Uterine artery embolization (UAE) is an effective minimally invasive treatment for adenomyosis (AM). This study aimed to evaluate the clinical outcomes of UAE in patients with different AM subtypes according to the Kishi classifi…

BACKGROUND: Endometriosis (EMS) causes debilitating pain and reduces quality of life. Whether pelvic floor muscle training (PFMT) provides independent, additive benefits beyond standard postoperative hormonal suppression remains unknown. M…

OBJECTIVE: To compare postoperative sexual function outcomes following vaginal natural orifice transluminal endoscopic surgery (vNOTES) and laparoscopic tubal sterilization (LTS). MATERIAL AND METHODS: This retrospective comparative cohort…

OBJECTIVE: To develop and validate a simple yet effective nomogram based on clinical and ultrasound factors for predicting the malignant risk of ovarian-adnexal masses and to evaluate its diagnostic performance and clinical utility. METHOD…

[This corrects the article DOI: 10.3389/fmed.2025.1635960.].

BACKGROUND: Endoscopic ultrasonography (EUS) is important for evaluating colorectal subepithelial lesions (SELs), but EUS-histopathology mismatch may complicate preoperative management. Evidence for predicting mismatch risk in colorectal SE…

INTRODUCTION: Nomograms are intuitive graphical tools that integrate multiple prognostic variables to generate individualized risk estimates. To date, no study has developed a validated prediction model specifically for symptomatic recurren…

INTRODUCTION: The identification of severe acute pancreatitis (SAP) is paramount for effective patient management, but the gold standard for diagnosing SAP requires over 48 h of organ failure, which may delay timely treatment. Hence, this s…

Diaphragmatic endometriosis is a rare and often underrecognized manifestation of extrapelvic endometriosis that may lead to severe complications such as diaphragmatic rupture or herniation. We report the case of a 42-year-old woman with a l…

INTRODUCTION: Subinvolution of the postpartum uterus is a common puerperal complication. While Chinese herbal hot compress (CHHC) therapy has been widely applied to promote postpartum uterine involution, its underlying mechanisms remain unc…

OBJECTIVE: Enhanced Recovery After Surgery (ERAS) protocols have been proven to optimize recovery in various surgical disciplines, including gynecologic surgery. However, their impact on laparoscopic hysterectomy for benign conditions remai…

OBJECTIVE: To evaluate the clinical efficacy of Xiaonang Yusi decoction (XNYSD, ) in patients with phlegm-dampness type polycystic ovary syndrome (PCOS) undergoing in vitro fertilization and embryo transfer (IVF-ET), and to investigate its …

BACKGROUND: Repeated implantation failure (RIF) is a key challenge in assisted reproductive technology (ART), and its mechanism is closely related to Endometrial receptivity (ER). Although the effects of some Endometrial receptivity paramet…

OBJECTIVE: Abnormal uterine bleeding (AUB) is one of the leading causes of gynecological consultations and indications for hysterectomy. The aim of this study is to determine the distribution of aetiological causes in patients undergoing hy…

BACKGROUND: There is not enough radiologic data in the literature for the quantitative value of uterine stiffness and this study aims to contribute to the literature in this field. OBJECTIVE: To evaluate the feasibility of measuring uterin…