Sylvie Defrère

No ORCID on file · 32 papers in corpus · active 2005-2014

Study types

  • article 25
  • review 7

Condition tags

  • endometriosis 31
  • infertility 3
article 2008
Unsuccessful Induction of Endometriosis in Female Rhesus Macaques (Macaca mulatta)
Gynecologic and obstetric investigation ·doi:10.1159/000127447

BACKGROUND/AIMS: The aim of this study was to induce endometriosis in female rhesus macaques (Macaca mulatta) for research purposes. METHODS: Three female monkeys from 4 to 4.5 years of age underwent three consecutive attempts at endometrio…

article 2007
Agents Blocking the Nuclear Factor-κB Pathway Are Effective Inhibitors of Endometriosis in an in vivo Experimental Model
Gynecologic and obstetric investigation ·doi:10.1159/000111148

BACKGROUND: In vitro studies suggest that the transcription factor nuclear factor-kappa B (NF-kappaB) is implicated in the transduction of proinflammatory signals in endometriosis. The aim of this study was to investigate the involvement of…

article 2007
Increased activation of nuclear factor-kappa B (NF-κB) in isolated peritoneal macrophages of patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.06.015
article 2007
Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gam033

Red (active), black and white endometriotic lesions are characteristic of peritoneal endometriosis. The transcription factor nuclear factor-kappa B (NF-kappaB) activates proinflammatory, proliferative and antiapoptotic genes in many cell ty…

article 2006
Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model
Human Reproduction ·doi:10.1093/humrep/del261

BACKGROUND: Iron deposits are characteristic of endometriotic lesions, and pelvic iron concentrations are higher in endometriosis patients than in women without endometriosis. In this study, the effect of iron overload and iron chelation on…

article 2006
Quantification of endometriotic lesions in a murine model by fluorimetric and morphometric analyses
·doi:10.1093/humrep/del115
article 2005
Quantification of endometriotic lesions in a murine model by fluorimetric and morphometric analyses
Human Reproduction ·doi:10.1093/humrep/dei387

BACKGROUND: In animal models of endometriosis, the identification and quantification of lesions originating from human endometrium is often hampered by the small size of the implants and their embedding in murine tissue. The purpose of the …