Leng JH

No ORCID on file · 79 papers in corpus · active 2002-2025

Study types

  • article 60
  • other 10
  • review 4
  • case-report 2
  • letter 1

Condition tags

  • endometriosis 70
  • dysmenorrhea 22
  • adenomyosis 20
  • endometrioma 17
  • chronic_pelvic_pain 15
  • die_deep_infiltrating 11
  • infertility 10
  • dyspareunia 8
  • bowel_endometriosis 2
  • thoracic_endometriosis 1
other 2025
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20250529-00244
rct 2024
Chinese journal of integrative medicine ·doi:10.1007/s11655-024-3756-y

OBJECTIVE: To assess the efficacy and safety of Sanjie Analgesic Capsule (SAC) in Chinese patients with endometriosis-associated pain. METHODS: This was a multicenter, randomized, double-blind, placebo-controlled trial conducted at 15 cent…

article 2023
Annals of medicine ·doi:10.1080/07853890.2023.2243825

OBJECTIVE: To explore potential biomarkers indicating endometriosis (EM). MATERIALS AND METHODS: A proteomics method and combined quantitative transcriptomics were adopted to highlight markers in the EM. Venn analysis was used to integrate…

article 2023
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2023.102572

BACKGROUND: When ovarian endometrioma coexist with adenomyosis, the risk of postoperative recurrence increased. How is the effect of levonorgestrel-releasing intrauterine system (LNG-IUS) on symptomatic recurrence for those patients was unk…

other 2022
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20220427-00329
other 2021
Frontiers in medicine ·doi:10.3389/fmed.2021.696374

Objective: To investigate the difference of clinical features and outcomes between EM patients with and without AM after following up for at least 6 years after surgery. Methods: We retrospectively analyzed 358 EM patients who had a minimum…

article 2021
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20211009-00576

levels and more severe pelvic adhesions. Although there are no significant differences in the total recurrence rate and the recurrence rate of various types between the two groups, the proportion of pain recurrence in the DIE group is highe…

article 2021
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20211009-00574

子宫内膜异位症(内异症)是育龄期女性的常见病、慢性病,是雌激素依赖性疾病,是进展型的疾病。随着近年来内异症临床研究和基础研究的不断深入,对内异症的认识也在不断地更新。新的诊治观念包括提高对内异症的认识,早诊断早治疗,以延缓疾病的进展;根据不同的临床问题、不同的年龄阶段进行分层处理,综合评估,选择适宜的治疗方法,掌握手术指征,规范手术操作;保护卵巢功能,促进妊娠;术后长期管理,减少复发,改善生活质量;强调手术治疗的优缺点,手术决策需权衡各种风险及获益;强调药物管理在长期管理中的…

case-report 2021
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20201029-00806
article 2021
Current medical research and opinion ·doi:10.1080/03007995.2021.1885363

OBJECTIVE: Thoracic endometriosis syndrome (TES) is a rare disease in which a functioning endometrial tissue is observed in the pleura, lung, parenchyma, airways, and/or diaphragm. The optimal management of this disease remains a matter of …

article 2020
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20191213-00669

At presents, the diagnosis and treatment of endometriosis in China has been greatly improved, but the implementation of guidelines and the new concept is still a long-term job. The specialist clinic are held only in a few hospitals. It's th…

review 2020
Biology of reproduction ·doi:10.1093/biolre/ioaa124

An ideal research model plays a vital role in studying the pathogenesis of a disease. At present, the most widely used endometrial disease models are cell lines and animal models. As a novel studying model, organoids have already been appli…

review 2020
Chinese medical journal ·doi:10.1097/cm9.0000000000000885

Endometriosis is a prevalent chronic disease that affects approximately 6% to 10% of reproductive-aged women. Although numerous researchers have endeavored to explore the etiology of endometriosis over a century, its etiology still remains …

article 2020
Advances in therapy ·doi:10.1007/s12325-020-01299-w

IntroductionOvarian endometriosis is the most common type of endometriosis (EM), affecting more than 40% of women with EM. Currently, surgical intervention is still controversial in infertile patients with ovarian endometriosis, especially …

article 2020
Archives of gynecology and obstetrics ·doi:10.1007/s00404-020-05843-5

PurposeHere, we compared endometrioma recurrence rates in patients who have undergone a laparoscopic cystectomy and treated with a gonadotropin-releasing hormone agonist (GnRHa) alone or a GnRHa combined with a levonogestrel intrauterine sy…

other 2019
Journal of pain research ·doi:10.2147/JPR.S212117

PURPOSE: Our study aims to investigate the distribution of pain symptoms and the association between pain symptoms and clinical parameters in patients with adenomyosis. PATIENTS AND METHODS: The clinical and pathological data of 291 patien…

article 2019
Chinese medical journal ·doi:10.1097/cm9.0000000000000195

To the Editor: Endometriosis refers to the endometrial tissue (interstitial substance and gland) with growth function occurring in the uterine lining of uterine cavity and the places outside myometrium. It often leads to pain, infertility, …

letter 2018
Chinese medical journal ·doi:10.4103/0366-6999.243572

To the Editor: Uterine adenomyosis (AM) is caused by the ectopic growth of endometrial glands and stroma in the myometrium of the uterus, accompanied by hyperplasia and hypertrophy of the surrounding smooth muscle cells, leading to a diffus…

article 2018
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2018.10.006

The use of GnRH-a preoperatively may have a negative effect on natural pregnancy rates of patients after surgery with ovarian endometriomas.

article 2018
Chinese medical journal ·doi:10.4103/0366-6999.226070

BACKGROUND: Endometriosis is a challenging disease with symptoms such as dysmenorrhea and infertility. However, its etiology is still vague and there is still no effective markers or treatment. This study aimed to profile the circular RNAs …

article 2018
Chinese medical journal ·doi:10.4103/0366-6999.232790

BACKGROUND: When considering the issue of recurrence, perimenopausal women may have more dilemma during management comparing with young women, for example, whether to retain the uterus and ovary during surgery, whether it is necessary to ad…

2018
Journal of ovarian research ·doi:10.1186/s13048-018-0405-0

BackgroundSynchronous endometrial disorders have been poorly studied in women with endometrioid borderline ovarian tumors (EBOT). The aims of this study were to investigate the risk of endometrial disorders among women with EBOT and associa…

article 2017
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2017.08.005

The occurrence of pelvic mass after hysterectomy is tightly related to prior histologic findings, and particularly for ovarian endometrioma. Higher number of prior abdominal surgery will exacerbated the risk. It is effective to prevent the …

article 2017
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2017.02.002
other 2017
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567X.2017.05.004

Objective: To evaluate different postoperative medications as maintenance treatment for rectovaginal endometriosis (RVE) patients after conservative surgery. Methods: RVE patients who underwent transvaginal partial excision from January 200…