Yokoi A

No ORCID on file · 13 papers in corpus · active 2017-2026

Study types

  • article 4
  • review 2
  • other 1

Condition tags

  • endometriosis 7
  • infertility 1
  • endometrioma 1
review 2026
Communications medicine ·doi:10.1038/s43856-026-01704-5

Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting pathogen…

2025
Cancers ·doi:10.3390/cancers17020184

Background/objectivesS100A4, a small calcium-binding protein, promotes metastasis in a variety of human malignancies, but little is known about its involvement in ovarian clear cell carcinoma (OCCC). Herein, we characterized the functional …

other 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1442684

INTRODUCTION: Endometriosis can cause of infertility, and evaluation methods for predicting clinical pregnancy outcomes are desired. Extracellular vesicles (EVs) exist in blood and it contains small non-coding RNAs (ncRNAs) that may reflect…

review 2023
iScience ·doi:10.1016/j.isci.2023.108739

The pathogenesis of endometriosis is a complex process, and recent research has introduced novel hypotheses in this field. This review summarizes recent studies on the pathogenesis of endometriosis. We focused on several classical hypothese…

2023
Molecular oncology ·doi:10.1002/1878-0261.13503

Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is a scaffold protein that is required for epithelial polarity. Knockout (KO) of membranous EBP50 (Me-EBP50) in ovarian clear cell carcinoma (OCCC) cells induced an epithelial-mesenchym…

article 2023
Reproductive biology ·doi:10.1016/j.repbio.2023.100821

Ovarian endometrioma (OE) is a common gynecological disease that is often treated with surgery and hormonal treatment. However, ovarian cystectomy can impair the ovarian reserve (OR). Previously, we showed that perioperative administration …

article 2020
F&S science ·doi:10.1016/j.xfss.2020.09.001

Objective To establish and characterize cell lines derived from human endometrial epithelial cells (ECs) and mesenchymal cells (MCs) from patients with and without endometriosis. Design In vitro experimental study. Setting University and na…

2020
Cancer science ·doi:10.1111/cas.14599

Ovarian cancer is the most lethal gynecological cancer due to lack of early screening methods and acquired drug resistance. MicroRNAs (miRNAs) are effective post-transcriptional regulators that are transferred by extracellular vesicles, suc…

article 2019
Human pathology ·doi:10.1016/j.humpath.2019.04.001

We focused on specific molecular events during the development of endometriosis-associated ovarian endometrioid carcinoma (OEmCa) and ovarian clear cell carcinoma (OCCCa). Alterations in β-catenin (encoded by CTNNB1) and microsatellite inst…

article 2019
BMC cancer ·doi:10.1186/s12885-019-5539-y

BACKGROUND: Expression of Nodal, a member of the TGF-β superfamily, is commonly absent in differentiated tissues, while its re-expression occurs in a variety of human malignancy. However, little is known about its involvement in ovarian tum…

2017
Oncotarget ·doi:10.18632/oncotarget.20688

Ovarian cancer is the leading cause of gynecologic cancer mortality, due to the difficulty of early detection. Current screening methods lack sufficient accuracy, and it is still challenging to propose a new early detection method that impr…

2017
Cell communication and signaling : CCS ·doi:10.1186/s12964-017-0211-0

BackgroundThe left-right determination factor (LEFTY) is a novel member of the TGF-β/Smad2 pathway and belongs to the premenstrual/menstrual repertoire in human endometrium, but little is known about its functional role in endometrial carci…

2017
Oncotarget ·doi:10.18632/oncotarget.18882

To identify proteins involved in ovarian clear cell carcinoma (OCCCa), shotgun proteomics analysis was applied using formalin-fixed and paraffin-embedded samples of ovarian carcinoma. Analysis of 1521 proteins revealed that 52 were differen…