Huang E

No ORCID on file · 7 papers in corpus · active 2023-2026

Study types

  • article 2
  • other 1
  • preprint 1
  • review 1

Condition tags

  • endometriosis 5
  • infertility 1
  • adenomyosis 1
article 2026
Single-cell profiling and machine learning identify cuproptosis-related fibroblast subpopulations and fibrogenesis modulator AEBP1 in endometriosis
Apoptosis : an international journal on programmed cell death ·doi:10.1007/s10495-026-02342-x

Endometriosis is characterized by progressive fibrosis and limited therapeutic options. Cuproptosis, a copper-dependent form of regulated cell death, has been implicated in multiple pathological conditions, but its relevance to fibroblast-m…

article 2025
Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis
Scientific reports ·doi:10.1038/s41598-025-22400-9

Endometriosis is a common disease among women of childbearing age, and endoplasmic reticulum stress (ERS), a response involved in regulating protein homeostasis, has been linked to its pathogenesis. To identify ERS-related hub genes, this s…

preprint 2024
Bioinformatic analysis reveals endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis：implications for disease subtyping and therapeutic strategies
·doi:10.21203/rs.3.rs-4212798/v1

Abstract Background Numerous investigations have demonstrated the implication of endoplasmic reticulum stress (ERS) in the etiology of endometriosis. Employing bioinformatics methodologies, we conducted an analysis to ascertain the particip…

2024
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Communications biology ·doi:10.1038/s42003-024-06960-6

LncRNAs are highly implicated in oxidative stress (OS) during the growth of mammalian follicles. TAK1 binding protein 2 gene (TAB2) has been suggested to involve in the normal apoptosis and proliferation of granulosa cells (GCs), the main s…

2024
The Immunosuppressive Receptor CD32b Regulation of Macrophage Polarization and Its Implications in Tumor Progression.
International journal of molecular sciences ·doi:10.3390/ijms25179737

Macrophages, pivotal components of the immune system, orchestrate host defense mechanisms in humans and mammals. Their polarization into classically activated macrophages (CAMs or M1) and alternatively activated macrophages (AAMs or M2) dic…

other 2023
GRIK1-AS1 deficiency accelerates endometriosis progression by boosting DNMT1-dependent SFRP1 promoter methylation in endometrial stromal cells
The journal of gene medicine ·doi:10.1002/jgm.3557

BACKGROUND: Endometriosis, a gynecological disease that affects up to 10% of women, is a major cause of pain and infertility. Deregulation of the epigenome is accountable for the onset and progression of endometriosis, although its exact me…

review 2023
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology
Cell communication and signaling : CCS ·doi:10.1186/s12964-023-01078-4

Gene expression and posttranscriptional regulation can be strongly influenced by epigenetic modifications. N6-methyladenosine, the most extensive RNA modification, has been revealed to participate in many human diseases. Recently, the role …