Joyce Y. Tung

No ORCID on file · 8 papers in corpus · active 2017-2023

Study types

  • meta-analysis 2
  • preprint 2
  • review 2
  • article 1
  • erratum 1

Condition tags

  • endometriosis 8
  • infertility 2
meta-analysis 2023
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Nature genetics ·doi:10.1038/s41588-023-01323-z

Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genom…

erratum 2022
Author Correction: Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
Nature communications ·doi:10.1038/s41467-022-33222-y
review 2021
Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways
Human Reproduction ·doi:10.1093/humrep/deab254

STUDY QUESTION: Is there a shared genetic or causal association of endometriosis with asthma or what biological mechanisms may underlie their potential relationships? SUMMARY ANSWER: Our results confirm a significant but non-causal associat…

article 2020
Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality
Human genetics ·doi:10.1007/s00439-020-02223-6
review 2019
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
Nature communications ·doi:10.1038/s41467-019-12536-4

Abstract Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity and high economic burden. Here we conduct a GWAS meta-analysis in 35,474 …

preprint 2018
Genome-wide association analysis identifies 27 novel loci associated with uterine leiomyomata revealing common genetic origins with endometriosis
·doi:10.1101/324905

Uterine leiomyomata (UL), also known as uterine fibroids, are the most common neoplasms of the reproductive tract and the primary cause for hysterectomy, leading to considerable impact on women’s lives as well as high economic burden 1,2 . …

preprint 2018
Genome-wide association studies on endometriosis and endometriosis-related infertility
·doi:10.1101/401448

Abstract Endometriosis affects ∼10% of women of reproductive age. It is characterized by the growth of endometrial-like tissue outside the uterus and is frequently associated with severe pain and infertility. We performed the largest endome…

meta-analysis 2017
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
Nature communications ·doi:10.1038/ncomms15539

Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely unknown. Here we perform a meta-analysis of 11 genome-wide ass…