Pramathes DasMahapatra (3190542)

Hematoxylin and Eosin staining of ectopic endometriosis show presence of (A,D) endometrial glands (black arrow) and stroma(black asterisk), (B,E) hemorrhage and iron deposition (red asterisk) and (C,F) aberrant blood vessel formation(yellow…

Mouse model of endometriosis were developed by inoculation of endometrial cells into peritoneum of the recipient mice as described in the ‘material and methods’. MMP-2i (20mg/kg) and COX-2i (40mg/kg) were administrated every alternate day f…

(A) Immunofluorescence for Von Willebrand factor (red flourescence) in early and late stages (n = 3 samples/stage) of ovarian endometriosis. Nucleus was stained with DAPI (blue flourescence). (B) Immunohistochemistry for cycloxygenase-2 in …

(A,B) Status of MMP-2 activity in eutopic endometrium (n = 15 samples/group) between women with and without endometriosis. (C,D) Serum MMP-2 status in different stages of ovarian endometriosis patients. (E-G) Status of MMP-2 activity in ect…

Endometriosis is an inflammatory, proliferative disease with increased PGE2 responses. The production of PGE2 from arachidonic acid (A.A.) is regulated by cycloxygenase-2 (COX-2). The present study found that the COX-2-PGE2-pAKT axis is inv…

Representative western blots (A) and profiles for expressions of TIMP-2 (n = 14 samples/stage) and MT1MMP (n = 12 samples/stage) in ectopic ovarian endometriosis(B,C). Means ± SEM. p<0.05 was accepted as level of significance; *** p < 0.001…