Study types
- article 13
- other 4
- preprint 2
Condition tags
- endometriosis 17
- die_deep_infiltrating 9
- infertility 4
- dysmenorrhea 2
- dyspareunia 2
Top journals
Frequent coauthors
other
2024
Background: Deep endometriosis (DE) is a special form of endometriosis, one of the most common benign diseases in gynecology. In the specific case of DE, ectopic endometrium can be found not only in peritoneal but also in deeper tissue laye…
other
2024
Background: Endometriosis is known to be a common chronic disease that often affects the quality of life of patients. Especially for deep endometriosis (DE), the most challenging form of the disease, surgery remains an important component o…
other
2023
BACKGROUND: Adhesions after endometriosis resection are frequent and the most common causes for chronic pain and secondary infertility. Primary results of our randomized controlled trial (RCT) on adhesion prevention after deep infiltrating …
article
2022
Objective Multiple forms of endometriosis have been shown to harbour somatic cancer-driver alterations. Previous studies have focused on the inter-patient heterogeneity of genetic alterations in endometriosis, analyzing lesions collected fr…
article
2022
OBJECTIVE: To investigate the heterogeneity of somatic cancer-driver mutations within patients and across endometriosis types. DESIGN: A single-center cohort, retrospective study. SETTING: Tertiary specialist-care center at a university h…
article
2021
Abstract Purpose Adhesion formation after endometriosis surgery is a severe problem affecting up to 90% of patients. Possible complications include chronic pain, ileus, and secondary infertility. Therefore, effective adhesion prophylaxis is…
preprint
2021
Abstract Endometriosis symptoms are heterogeneous with controversy on whether it constitutes a single disease or multiple distinct types. Our previous work found recurrent somatic cancer-driver alterations in endometriosis; however, these h…
preprint
2021
Abstract ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumor suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory repo…
article
2021
Abstract ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumour suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory rep…
article
2020
Zielsetzung Bei bis zu 90% der Patientinnen kommt es nach Endometriose-Resektion zur Ausbildung von Adhäsionen. Diese wiederum können die Ursache für eine Vielzahl von Komplikationen sein, von denen die häufigsten Schmerzen, Darmobstruktion…
article
2020
Endometriosis has yielded controversy on whether it constitutes a single disease or distinct types. Current classification systems poorly correlate with the severity of symptoms and do not provide prognostic tools that can guide management …
article
2020
Zielsetzung Die chirurgische Therapie ist der Goldstandard in der Behandlung der TIE. Diese ist die anspruchsvollste und damit am schwierigsten zu behandelnde Endometrioseform. Unsere Untersuchung verfolgte das Ziel, den postoperativen Verl…
article
2019
other
2018
We aimed to validate the prognostic association of p16 expression in ovarian high-grade serous carcinomas (HGSC) and to explore it in other ovarian carcinoma histotypes. p16 protein expression was assessed by clinical-grade immunohistochemi…
article
2018
DIE is the most challenging type of endometriosis and may be associated with severe pain and infertility. Complete minimally invasive resection is the gold standard treatment, leading to pain relief and increased fertility in a high number …
article
2018
The clinical presentation of endometriosis is highly heterogeneous. In a landmark study we have shown somatic cancer-driver mutations in deep infiltrating endometriosis, with at least one case having multiple sites harboring the same driver…
article
2018
Endometriosis is a common gynecological disease and precursor of clear cell and endometrioid ovarian carcinomas. We recently demonstrated that one form of endometriosis with little malignant potential, deep infiltrating endometriosis (DE), …
article
2018
STUDY QUESTION: Does incisional endometriosis (IE) harbor somatic cancer-driver mutations? SUMMARY ANSWER: We found that approximately one-quarter of IE cases harbor somatic-cancer mutations, which commonly affect components of the MAPK/RAS…
article
2018
DIE is the most challenging type of endometriosis and laparoscopic surgery is considered gold standard. In order to achieve a complete resection extensive surgical procedures have to be performed in the majority of DIE patients. The aim of …