Kelk DA

No ORCID on file · 3 papers in corpus · active 2023-2024
2024
Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-024-03143-4

PurposeDetermine if the gene expression profiles of ovarian support cells (OSCs) and cumulus-free oocytes are bidirectionally influenced by co-culture during in vitro maturation (IVM).MethodsFertility patients aged 25 to 45 years old underg…

2023
hMG addition affects the change in progesterone level during IVF stimulation and LBR: a retrospective cohort study.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01150-1

BackgroundPremature progesterone (P) rise during IVF stimulation reduces endometrial receptivity and is associated with lower pregnancy rates following embryo transfer (ET), which can influence provider recommendation for fresh or frozen ET…

2023
Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dead205

Study questionCan in vitro maturation (IVM) and developmental competence of human oocytes be improved by co-culture with ovarian support cells (OSCs) derived from human-induced pluripotent stem cells (hiPSCs)?Summary answerOSC-IVM significa…