Sun H

ObjectiveTo compare the effects of frozen-thawed embryo transfer at different times after hysteroscopic endometrial polyp resection on pregnancy outcomes and to provide evidence for individualized clinical treatment.MethodsThis study was a …

ObjectiveTo investigate the impact of three endometrial preparation protocols-hormone replacement therapy (HRT), natural cycle (NC), and down-regulation HRT-on pregnancy outcomes in frozen embryo transfer (FET) cycles among patients with a …

The maternal-fetal interface is the core site of pregnancy occurrence and maintenance. Its complex physiological and pathological processes have long been concentrated in two-dimensional cell models and animal models. Organoids represent a …

BackgroundOocyte aneuploidy is a major cause of pregnancy failure in women of advanced maternal age (AMA), and current assisted reproductive technologies offer limited effective strategies to prevent age-related decline in oocyte quality. T…

BACKGROUND: The long noncoding RNA (lncRNA) FAM83H-AS1 plays a critical role in the development and progression of various cancers. This study evaluates the feasibility of serum FAM83H-AS1 as a diagnostic and staging marker for ovarian canc…

BackgroundThin endometrium continues to pose a significant challenge in assisted reproductive technology (ART) cycles, necessitating further exploration of therapeutic approaches. Tamoxifen (TMXF) has been primarily used in ovarian stimulat…

BackgroundPatients undergoing total laparoscopic hysterectomy (TLH) commonly experience postoperative pain and are at relatively high risk of postoperative nausea and vomiting (PONV). Tegileridine is a recently developed biased μ-opioid rec…

Various cellular processes, such as DNA repair and signal transduction, are regulated through ubiquitination and deubiquitination. Dysregulation of ubiquitination cascade enzymes and deubiquitinating enzymes leads to various diseases. Among…

BackgroundHepatocellular carcinoma (HCC) mainly develops in cases of fibrosis and cirrhosis and is accompanied by intestinal flora disorder. HCC also affects CD8+ T cell immune function. 5,7-Dimethoxyflavone (DMF), an active flavonoid with …

ObjectiveTo investigate the effects of cold environment exposure on female reproductive capacity and explore its potential regulatory mechanisms.MethodsFemale mice were subjected to cold water immersion to simulate cold environment exposure…

ObjectiveThe aim of this study is to assess the impact of different embryo transfer strategies, focusing on cleavage-stage embryos and blastocysts, on pregnancy and neonatal outcomes in frozen-thawed embryo transfer (FET) cycles among women…

BackgroundThe role of estrogen in liver cancer cells has attracted attention, but its specific actions and underlying mechanisms remain unclear.MethodsFlow CytoMetry and Western blotting were used to investigate the mechanism of HOXA11-AS a…

To analyze the global burden of pancreatitis in women of childbearing age (WCBA) at the global, regional and national levels from 1990 to 2021. Data for pancreatitis incidence and deaths in females aged 15 to 49 years were downloaded from t…

ObjectivesTo evaluate the impact of autologous platelet-rich plasma (PRP) intrauterine perfusion on endometrial receptivity and pregnancy outcomes in patients with implantation failure.MethodsThis retrospective cohort study included patient…

ObjectivesLOXL2, known as Lysyl oxidase-like 2, is classified as a lysyl oxidase (LOX) family member. However, its role and mechanism in endometrial cancer (EC) are unknown. Therefore, we aimed to investigate the potential role and mechanis…

ObjectiveThe impact of prophylactic salpingectomy on the prevention of epithelial ovarian cancer (EOC) remains unclear, particularly in Asian populations where data is lacking. In this systematic review and meta-analysis study, we sought to…

Research on circular RNA (circRNA) in poultry increasingly explores its role as a potential regulator in various diseases. It has also shown differential expression of circRNAs in infected tissues, signifying their participation in disease …

In this comprehensive review, we delve into the evolution of drug delivery systems in reproductive medicine with a focus on the emerging role of exosomes, a class of extracellular vesicles. Exosomes offer unique advantages in overcoming the…

Ovarian cancer(OC) is the second most common gynecological malignancy worldwide. While traditional treatments such as cytoreductive surgery, chemotherapy, and targeted drugs have made progress, patients with advanced disease still face high…

BackgroundSeveral studies have demonstrated that pre-treatment with long-acting Gonadotropin-Releasing Hormone agonists (GnRHa) can significantly enhance the clinical pregnancy rate among recurrent implantation failure (RIF) patients. Inves…

BackgroundThis study aimed to evaluate the clinical outcomes of umbilical cord mesenchymal stem cell (UC-MSC) transplantation on ovarian function in women with premature ovarian insufficiency (POI), and its potential to improve in vitro fer…

OBJECTIVES: To evaluate the association between healthy lifestyle behaviours and the incidence of irritable bowel syndrome (IBS). DESIGN: Population-based prospective cohort study. SETTING: The UK Biobank. PARTICIPANTS: 64 268 adults age…

As an important part of medical science, Traditional Chinese Medicine (TCM) attracts much public attention due to its multi-target and multi-pathway characteristics in treating diseases. However, the limitations of traditional research meth…

Background and objectivesInfertility is a pressing public health concern on a national scale and has been linked to inflammatory conditions. However, limited research has been conducted on the impact of the Dietary Inflammatory Index (DII) …

OBJECTIVE: We carried out this study to explore the possibility of initiating goserelin therapy during the non-menstrual period in patients diagnosed with adenomyosis. METHODS: 115 premenopausal adenomyosis patients were enrolled and divid…