K Takayama
No ORCID on file
· 13 papers in corpus
· active 1983-2019
Study types
- article 6
- review 4
- other 2
- peer-review 1
Condition tags
- endometriosis 13
Top journals
Frequent coauthors
peer-review
2019
Endometriosis is a chronic disease occurring during the reproductive stage of women.Although there is only limited association between endometriosis and gynecological cancers with regard to clinical features, the molecular basis of the rela…
article
2014
Conversion of C19 steroids to estrogens is catalyzed by aromatase in human ovary, placenta and extraglandular tissues such as adipose tissue, skin and the brain. Aromatase activity is not detectable in normal endometrium. In contrast, aroma…
article
2001
review
2000
review
2000
Conversion of C(19) steroids to estrogens is catalyzed by aromatase in human ovary, placenta and extraglandular tissues such as adipose tissue, skin and the brain. Aromatase activity is not detectable in normal endometrium. In contrast, aro…
other
2000
Although treatment of one unusually aggressive case of postmenopausal endometriosis with an aromatase inhibitor has been strikingly successful, large clinical trials are required to establish whether aromatase inhibitors will have a signifi…
review
1999
Estrogen is the most important known factor that stimulates the growth of endometriosis. Estrogen delivery to endometriotic implants was classically viewed to be only via the circulating blood in an endocrine fashion. We recently uncovered …
article
1999
In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu)2cAMP or PGE2 to give rise to physiologically significant estrogen biosynthesis. Since eutop…
article
1998
Aberrant aromatase expression in stromal cells of endometriosis gives rise to conversion of circulating androstenedione to estrone in this tissue, whereas aromatase expression is absent in the eutopic endometrium. In this study, we initiall…
article
1998
review
1997
Aromatase P450 (P450arom) is responsible for conversion of C19 steroids to estrogens in a number of human tissues, such as the placenta, gonads, adipose tissue, skin and the brain. Aromatase expression in human tissues is regulated by use o…
article
1997
C19 steroids are converted to estrogens by aromatase P450 (P450arom). Aromatase expression in humans is regulated by use of tissue-specific promoters in the placenta (promoter I.1), adipose tissue (promoters I.4, I.3, and II), and gonads (p…
other
1983
Immunosuppressive acidic protein(IAP) levels were measured in human sera by a single radial immunodiffusion using an IAP plate. Sera were obtained from healthy controls (79 females), patients with myoma uteri (53 cases), patients with benig…