Cao M

This cross-sectional study investigated galectin-1, -3, and -9 in adenomyosis. Analysis of hysterectomy tissues from premenopausal women via western blot, qPCR, immunohistochemistry, and Masson's staining revealed significantly elevated gal…

PURPOSE: Endometriosis and adenomyosis are both characterised by ectopic endometrial-like tissue growing outside the endometrium of the uterus, however, they are ultimately distinct diseases with different pathophysiological mechanisms. End…

BACKGROUND: Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease with multifactorial pathogenesis. Although polygenic risk scores (PRSs) have been developed to enable early prediction, their accuracy remains l…

Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent primary …

Nociplastic pain (NPP) is a recently defined form of chronic pain, characterized by altered nociception in the absence of clear evidence of nociceptive or neuropathic pain. It is believed to be driven by maladaptive changes in nociceptive p…

BackgroundHyperthyroidism adversely impacts female reproduction, yet its association with in vitro fertilization (IVF) outcomes remains controversial. It remains unknown whether ovarian function recovers upon achieving euthyroidism. We comp…

OBJECTIVE: To demonstrate laparoscopic identification and treatment of aberrant superior gluteal vein-related intrapelvic sciatic nerve compression using a targeted neurovascular decompression approach. DESIGN: Video article SETTING: A sin…

BACKGROUND: Prior research indicates a potential link between dyslipidemia and endometriosis (EMs). However, the relationship between remnant cholesterol (RC) and EMs has not been thoroughly investigated. Consequently, looking into and clar…

Epigenetic regulation of placental development and pregnancy-related disease processes has recently been a hot research topic. Implantation and subsequent placental development depend on carefully orchestrated interactions between fetal and…

Danggui Shaoyao San (DSS), a classical multi-herbal formulation of traditional Chinese medicine, demonstrates therapeutic potential for Type 2 Diabetes Mellitus (T2DM), Alzheimer's Disease (AD), and Polycystic Ovary Syndrome (PCOS). This re…

AbstractBackgroundThe potential modifiable factors influencing irritable bowel syndrome (IBS) have not been thoroughly documented. We aimed to systematically investigate the modifiable factors associated with IBS, while accounting for the i…

BackgroundInfertility is a public health issue closely related to obesity. However, the relationship between obesity-related indicators and infertility is currently uncertain. The present study aimed to explore the association between obesi…

PurposeThis study aimed to evaluate the comparative reproductive outcomes of ovarian stimulation combined with intrauterine insemination using partner's sperm (OS-IUI) in eumenorrheic and normogonadotropic oligomenorrheic women.MethodA retr…

ObjectiveTo investigate the implications of serum hsa_circ_0007534 levels in ovarian cancer (OC) patients.MethodsA retrospective analysis was conducted on the clinical data of 102 OC patients, and 102 healthy controls (HCs) were included in…

Environmental factors are the major contributor to the onset of immunological disorders such as ulcerative colitis. However, their identities remain unclear. Here, we discover that the amount of consumed L-Tryptophan (L-Trp), a ubiquitous d…

Endometriosis, a prevalent condition, has long been recognized as a chronic and debilitating ailment affecting an estimated 1790 million women worldwide. Observational studies have established a correlation between endometriosis and ovarian…

PurposeThe study aims to investigate whether chromosomal polymorphism affects embryo development and pregnancy outcomes of unexplained recurrent pregnancy loss (uRPL) couples undergoing PGT-A.MethodsA total of 585 couples with uRPL history …

ObjectiveThis study aimed to develop multiphase big-data-based prediction models of ovarian hyperstimulation syndrome (OHSS) and a smartphone app for risk calculation and patients' self-monitoring.MethodsMultiphase prediction models were de…

BACKGROUND: Intestinal obstruction caused by endometriosis maybe easily misdiagnosed as a tumor or other occupying disease in emergency condition. How to deal with it depending on the clarity of the preoperative diagnosis and the experience…

BackgroundVaccine hesitancy was found in couples seeking artificial reproductive technology (ART) services. As the main vaccine used in China, investigations into the influence of inactivated coronavirus disease 2019 (COVID-19) vaccines on …

Abstract Background Endometriosis is a common disease and was considered a chronic, debilitating disease affecting an estimated 1790 million women worldwide. Observational studies have shown a link between endometriosis and ovarian cancer. …

ObjectiveWe aimed to evaluate the future outcomes of patients undergoing their first IVF (in vitro fertilization) attempt with no oocyte retrieved, no normal zygotes formed, or no embryos available for transfer and to identify factors affec…

Study questionDo inactivated coronavirus disease-2019 (COVID-19) vaccines affect IVF outcomes among the vaccine recipients?Summary answerThe receipt of inactivated COVID-19 vaccines before ovarian stimulation has little effect on the outcom…

Study questionDoes inoculation with inactivated vaccines against coronavirus disease 2019 (Covid-19) before frozen-thawed embryo transfer (FET) affect live birth and neonatal outcomes?Summary answerInactivated Covid-19 vaccines did not unde…

The local Renin-Angiotensin System (RAS) has been demonstrated to exist in a wide range of tissues and organs, In the female reproductive system, it is mainly found in the ovary, uterus and placenta. The RAS system is made up of a series of…