Lawson C

No ORCID on file · 4 papers in corpus · active 2001-2008

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 4
other 2008
Abnormal interleukin 1 receptor types I and II gene expression in eutopic and ectopic endometrial tissues of women with endometriosis
Journal of reproductive immunology ·doi:10.1016/j.jri.2007.04.002

Interleukin-1 (IL1) is believed to play a central role in the immuno-inflammatory process associated with endometriosis. IL1 triggers cell activation via its receptor type I (IL1R1), but its receptor type II (IL1R2) is known instead as a sc…

article 2007
Imbalance in the expression of the activating type I and the inhibitory type II interleukin 1 receptors in endometriosis
Human Reproduction ·doi:10.1093/humrep/dem021

BACKGROUND: The ectopic establishment and progression of endometrial tissue is dependent upon its interaction with and responsiveness to the stimuli present in its new environment. Immune cell-derived cytokines, such as interleukin 1 (IL1),…

article 2007
Increased expression of interleukin-1 receptor type 1 in active endometriotic lesions
Reproduction (Cambridge, England) ·doi:10.1530/rep.1.01121

Abstract The establishment and progression of ectopic endometrial implants are dependent upon their interaction with and responsiveness to the stimuli present in their new environment. According to our and other previous studies, immune cel…

article 2001
Ectopic endometrial cells express high concentrations of interleukin (IL)-8 in vivo regardless of the menstrual cycle phase and respond to oestradiol by up-regulating IL-1-induced IL-8 expression in vitro
Molecular human reproduction ·doi:10.1093/molehr/7.9.859

Endometriosis, an oestrogen-dependent disorder affecting women of reproductive age, is associated with active angiogenesis and an increased recruitment of leukocyte into the peritoneal cavity where the implants often develop. The role of oe…