Yang Y

ObjectiveTo explore the correlation between autoantibodies, ultrasonic endometrial receptivity parameters and early miscarriage in recurrent spontaneous abortion (RSA) patients during subsequent pregnancies, and to establish and validate a …

Background and objectivePoly(ADP-ribose) polymerase inhibitors (PARPis) have fundamentally changed the treatment paradigm for patients with ovarian cancer, especially in tumors with homologous recombination deficiency (HRD). However, acquir…

Uterine infertility is a substantial global health challenge, imposing profound physical and emotional burdens on affected individuals, with endometrial injury being a key contributing factor. In this study, we report that platelet-derived …

BACKGROUND: In clinical practice, repeated oocyte retrieval cycles are often necessary for patients with diminished ovarian reserve (DOR). It has been hypothesized that the mechanical stimulation from the initial oocyte pick-up (OPU) proced…

Yang Jin,1,* Yongchao Pan,2,* Yilai Bao,1 Fei Xu,1 Yun Yang,1 Jingwen Fan,1 Yidan Jin,1 Yong Zhou,1 Ruijin Wu1,3 1Department of Obstetrics and Gynecology, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang,…

ObjectiveWomen with premenstrual disorder (PMD) display heightened sensitivity to hormonal changes and may be at risk for psychiatric disorders during other hormonally dynamic periods such as pregnancy and postpartum. While PMD has been lin…

Ultraviolet (UV) radiation is a primary environmental factor responsible for skin photodamage, and exposure to UV rays is strongly linked to a variety of skin diseases. This study examined the prophylactic and therapeutic effects of Seed Oi…

BackgroundThe impact of the interval between consecutive testicular sperm aspiration (TESA) procedures on pregnancy outcomes of intracytoplasmic sperm injection (ICSI) in patients with obstructive azoospermia (OA) remains controversial. Thi…

ObjectiveTo describe the short-term safety, procedural characteristics, and clinical outcomes of ovarian vein embolization with adjunctive local sclerotherapy in a selected subgroup of women with pelvic venous disorder presenting with vulva…

During spaceflight, the female reproductive system undergoes substantial adaptation to microgravity and faces an increased risk of reproductive impairment. Mammalian oocytes remain arrested for extended periods at the first meiotic prophase…

This systematic review and Bayesian network meta-analysis assessed the diagnostic accuracy of wearable digital technology (WDT) in monitoring women's fertility window compared to conventional methods. 8 databases were searched until January…

Abstract Objectives: To evaluate the efficacy of gonadotropin-releasing hormone agonist (GnRHa) combined with lauromacrogol sclerotherapy in preserving ovarian reserve and reducing pain in patients with ovarian endometriotic cysts (OECs). M…

BackgroundUreteral reimplantation (UR) is the standard treatment for distal ureteral stricture, yet postoperative anastomotic restenosis impairs outcomes, with conventional imaging unable to quantify urinary tract obstruction and dysfunctio…

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS…

Various cellular processes, such as DNA repair and signal transduction, are regulated through ubiquitination and deubiquitination. Dysregulation of ubiquitination cascade enzymes and deubiquitinating enzymes leads to various diseases. Among…

Mitochondrial dysfunction has been implicated in the pathophysiology of endometriosis, but the role of ubiquitin-specific protease 2 (USP2) remains unclear. This study aimed to determine whether USP2 modulates mitochondrial respiratory acti…

BackgroundThe benefit of adjuvant chemotherapy for stage I ovarian endometrioid carcinoma (OEC) remains controversial. Hence, the study sought to explore its value in stage I OEC patients.MethodsStage I OEC patients (1988-2018) were identif…

Ovarian cancer (OC) remains a highly lethal gynecologic malignancy characterized by substantial molecular heterogeneity and diagnostic challenges. Although many reviews examine specific aspects of OC biology or treatment, few attempt to con…

To identify the factors affecting adverse reproductive outcomes in TPOAb-positive patients and to establish a predictive model based on these factors to assess the risk of adverse reproductive outcomes in patients. A retrospective cohort st…

BackgroundLung cancer is a prevalent form of cancer worldwide, presenting a substantial risk to human well-being. Lung cancer is classified into two main types: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). The advan…

Endometriosis is an uncommon condition, and its occurrence in the urachus is exceptionally rare. This case report highlights the extreme rarity of bladder endometriosis involving the urachal area. To the best of our knowledge, no such cases…

Magnetic nanomaterials (MNMs) are nanoscale materials with inherent magnetic properties that can respond to external magnetic fields, typically composed of magnetic metals or metal oxides. These materials exhibit broad application prospects…

BACKGROUND: Excessive exposure to heavy metals has been linked to various health problems, including organ damage, neurological disorders, and reproductive and developmental abnormalities. However, the relationship between heavy metals expo…

ObjectiveTo investigate the relationship between protein-rich foods, various nutritional supplements, and age of natural menopause and its symptoms.MethodsThis study was a large-scale cross-sectional survey. A multi-stage stratified random …