The Impact of Gonadotropin-releasing Hormone Agonist Combined with Lauromacrogol on Ovarian Reserve Function and Pain Scores in Patients with Ovarian Endometriotic Cysts

Zhang-wei Song, Lie Ma, Yan Yang, Lingling Lin
In: Gynecology and Minimally Invasive Therapy · 2026 · vol. 15(2) , pp. 127–131 · doi:10.4103/gmit.gmit-d-25-00008 · W7130653495
article OA: diamond CC0 ⤵ 1 in-corpus citation
🔓 Open OA copy View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found that gonadotropin-releasing hormone agonist combined with lauromacrogol sclerotherapy improved ovarian reserve function, reduced pain, and lowered recurrence rates in patients with ovarian endometriotic cysts compared to laparoscopic cystectomy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Abstract Objectives: To evaluate the efficacy of gonadotropin-releasing hormone agonist (GnRHa) combined with lauromacrogol sclerotherapy in preserving ovarian reserve and reducing pain in patients with ovarian endometriotic cysts (OECs). Materials and Methods: Eighty OEC patients (Oct 2020–Oct 2024) were randomized into two groups ( n = 40 each). The control group received laparoscopic cystectomy, and the observation group was treated with GnRHa plus lauromacrogol sclerotherapy. Curative effects were compared. Results: The total effective rate of the observation group (95.00%, 95% CI: 87.2–98.9) was higher than that of the control group (77.50%, 95% CI: 65.1–86.8; OR=5.51, 95% CI: 1.21–15.56, P < 0.05). After treatment, serum FSH, LH, E2, CA125, CA199 levels and VAS scores in the observation group were lower than those in the control group (all P < 0.05). The recurrence rate of the observation group (5.00%) was lower than that of the control group (17.<0.05). Conclusion: The combination of GnRHa and lauromacrogol sclerotherapy has a significant effect on OEC, which can improve ovarian reserve function, reduce pain scores and recurrence rates.

My notes (saved in your browser only)

Outcome instruments

VAS-pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (13)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK