Prostaglandin levels in the human endometrium were determined on day 2 of the menstrual cycle in eumenorrheic subjects and in patients with menorrhagia, dysmenorrhea, or both. Menorrhagic subjects had significantly higher levels of endometr…
Late proliferative (days 9 to 14) and midsecretory (days 18 to 24) human endometria were maintained in organ culture in the presence of 17 beta-estradiol and/or progesterone or mefenamic acid 17 beta-estradiol (0.1 to 1,000 ng/ml) increased…
Danazol inhibited chorionic gonadotropin-stimulated progesterone production by pregnant rat luteal cells in vitro in a dose-dependent fashion. Spectral studies indicated that the inhibition was a consequence of danazol's interfering with th…
The effect of danazol on progesterone (P4) and estradiol-17 beta (E2) secretion by cultured porcine granulosa cells was studied. Danazol markedly inhibited both basal and luteinizing hormone (LH)-stimulated P4 secretion by both granulosa an…