Adenomyosis (AM) is an estrogen-dependent gynecological disorder in which local steroid handling may contribute to clinical heterogeneity. To characterize estrogen metabolic features in AM, we used liquid chromatography-tandem mass spectrom…
OBJECTIVE: This study aims to assess the diagnostic efficacy of using a combination of ultrasonic probes including convex array probe, linear array probe, and intracavitary probe, for the detection of adenomyosis at the gallbladder fundus. …
Leiomyomas (LM) and adenomyosis (AM) are common gynecological diseases with high incidence rates and an increasing trend of affecting younger women. Accurate detection and differentiation of LM and AM in ultrasound images are crucial for se…
OBJECTIVE: To evaluate the effectiveness of various medications for the treatment of endometriosis-related pain through a network meta-analysis. DATA SOURCES: A comprehensive search was conducted in PubMed, Embase, Web of Science, and the …
(Abstracted from Obstet Gynecol 2025;146(2):e23-e35) An estimated 10% to 15% of women who are of reproductive age are affected by endometriosis, defined as abnormal growth of endometrium-like tissue outside of the uterus. Symptoms can inclu…
Low-grade serous ovarian carcinoma (LGSOC) is a rare subtype of ovarian cancer that accounts for approximately 6% to 10% of serous ovarian cancers. The clinical treatment of LGSOC is similar to that of high-grade serous ovarian carcinoma, h…
Abstract Uterine peristalsis, characterized by spontaneous slow-wave contractions of the subendometrial layer of the uterine myometrium, occurs throughout the menstrual cycle. Disruptions in peristalsis patterns may occur in women experienc…
OBJECTIVE: To study whether transvaginal ultrasound (TVUS) affected the uterine peristalsis (UP) patterns in nonpregnant participants. DESIGN: Institutional review board-approved, prospective observational cohort study. The noninvasive UP …
Cervical softening and dilation are critical for the successful term delivery of a fetus, with premature changes associated with preterm birth. Traditional clinical measures like transvaginal ultrasound and Bishop scores fall short in predi…
BACKGROUND: Ovarian endometrioid carcinoma (OEC) is the second most commonly occurring ovarian epithelial malignancy, but the associated prognostic factors remain obscure. This study aimed to analyze independent prognostic factors for patie…
This study aims to investigate the feasibility of multi-parametric MRI in distinguishing endometrioma from other ovarian cystic lesions. A total of 50 patients with clinically suspected endometriosis were recruited in the study. Quantitativ…
Throughout the menstrual cycle, spontaneous mild contractions in the inner layer of the uterine smooth muscle cause uterine peristalsis, which plays a critical role in normal menstruation and fertility. Disruptions in peristalsis patterns m…
BACKGROUND: Previous investigations have reported that controlling nutritional (CONUT) status scores, incorporating total cholesterol (TC) and serum albumin (SA) values, and total lymphocyte (LY) counts, are reliable malignant tumor predict…
BACKGROUND: Identifying and locating endometriotic lesions is crucial for preoperative planning, so new magnetic resonance imaging (MRI) techniques are urgently needed to improve the diagnostic sensitivity for pelvic endometriosis. PURPOSE…
We report a case of primary ovarian Burkitt lymphoma that occurred in a 25-year-old woman. The patient complained of a mass in the right ovary discerned by physical examination 2 months prior. Ultrasound examination indicated that the right…
PURPOSE: To examine the screening history of vaginal intraepithelial neoplasia (VaIN) and vaginal cancer. PATIENTS AND METHODS: We included women with histologically confirmed VaIN or vaginal cancer by colposcopy-directed biopsy between 1 …
BACKGROUND: With the improvement of bacterial detection, the theory of the sterile female upper reproductive tract has been frequently challenged in recent years. However, thus far, no researchers have used ovaries as study targets. METHOD…
Recently, the research on early detection of precancerous change and endometrial carcinoma has been focusing on minimally invasive procedures for screening. On this basis, we aim to verify the feasibility of endometrial samplers for screeni…
Objective: Chronic endometritis can be associated with abnormal uterine bleeding and infertility. The “gold standard” of diagnosing chronic endometritis is the identification of plasma cells, but this can be difficult. Immunohistochemical s…
Our previous work has demonstrated that interleukin-22 (IL-22) enhances the invasiveness of endometrial stromal cells (ESCs) of adenomyosis in an autocrine manner. In the present study, we further investigated whether IL-22 mediated crossta…
BACKGROUND: As a Chinese Traditional Medicine product, Kuntai capsule could improve the peri-menopausal symptoms in postmenopausal women. But it is still not clear whether Kuntai capsule has a good effect on alleviating peri-menopausal symp…
AIM: To evaluate the efficacy of combined laparoscopy and hysteroscopy compared with traditional uterine curettage in removing the ectopic conceptus and repairing the tissue defect following uterine artery embolization (UAE) management of c…
It has reported that interleukin-22 (IL-22) promotes the invasion of tumor cells. IL-22 in the endometriotic milieu stimulates the proliferation of human endometrial stromal cells (ESCs). The present study aimed to elucidate whether and how…
OBJECTIVE: To investigate the effect of yikun neiyi wan (YKNYW) and gestrinone on the expression of aromatase P450 (P450arom), cyclo-oxygenase-2 (COX-2) and estrogen receptor (ER) in isolated ectopic and normal endometrial stroma cells in v…