Multi-Parametric MRI in Diagnosing Ovarian Endometrioma: a Feasibility Study

In: ISMRM Annual Meeting · 2023 · doi:10.58530/2022/3151 · W4385554646
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Quantitative multi-parametric MRI, including T1, T2, T2*, and CEST mapping, accurately distinguishes endometriomas from other ovarian cysts with high AUC values.

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This feasibility study evaluated whether multi-parametric MRI could distinguish ovarian endometrioma from other ovarian cystic lesions in 50 patients with clinically suspected endometriosis, using quantitative T1 and T2 mapping, T2* mapping, and CEST. The authors reported a positive correlation between R2* and iron levels in endometrioma fluid, and high diagnostic performance with AUCs of 0.941 for R2*, 0.996 for T1, 0.980 for T2, and 0.806 for MTR_asym. The study’s main limitation is its small, feasibility design based on a recruited cohort rather than a large independent validation. This paper is centrally about endometriosis — specifically the use of multi-parametric quantitative MRI to diagnose ovarian endometrioma.

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Abstract

This study aims to investigate the feasibility of multi-parametric MRI in distinguishing endometrioma from other ovarian cystic lesions. A total of 50 patients with clinically suspected endometriosis were recruited in the study. Quantitative MRI, including T1, T2 mapping, T2* mapping and CEST, was used. A positive correlation was found between R2* and iron levels in fluid of endometrioma. The AUC of R2*, T1, T2 and MTR_asym were 0.941, 0.996, 0.980 and 0.806, respectively. Therefore, multi-parametric quantitative MRI can be considered an effective method in differentiating endometriomas from various ovarian cystic lesions.
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Abstract #3151 Multi-Parametric MRI in Diagnosing Ovarian Endometrioma: a Feasibility Study Fang Wang1, Dawei Ding2, Weiqiang Dou3, Dmytro Pylypenko3, Qing Wang1, and Dexin Yu1 1Department of Radiology, Qilu Hospital of Shandong University, Jinan, China, 2Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China, 3GE Healthcare, Beijing, China Synopsis This study aims to investigate the feasibility of multi-parametric MRI in distinguishing endometrioma from other ovarian cystic lesions. A total of 50 patients with clinically suspected endometriosis were recruited in the study. Quantitative MRI, including T1, T2 mapping, T2* mapping and CEST, was used. A positive correlation was found between R2* and iron levels in fluid of endometrioma. The AUC of R2*, T1, T2 and MTR_asym were 0.941, 0.996, 0.980 and 0.806, respectively. Therefore, multi-parametric quantitative MRI can be considered an effective method in differentiating endometriomas from various ovarian cystic lesions. How to access this content: For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library. After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library. After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers. Click here for more information on becoming a member.

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endometriosisendometrioma

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