Gentaro Izumi

No ORCID on file · 46 papers in corpus · active 2011-2026

Study types

  • article 33
  • other 6
  • preprint 3
  • case-report 2
  • book-chapter 1

Condition tags

  • endometriosis 31
  • mesh:D004715 24
  • endometrioma 14
  • adenomyosis 9
  • dysmenorrhea 3
  • infertility 2
  • thoracic_endometriosis 1
  • die_deep_infiltrating 1
  • bladder_endometriosis 1
  • mesh:D004412 1
article 2026
·doi:10.1016/j.rbmo.2026.105699

RESEARCH QUESTION: Does adenomyosis increase the risk of thromboembolic events, including both arterial and venous thromboembolism, compared with endometriosis, and what clinical factors may contribute to this association? DESIGN: This retr…

other 2026
Journal of the Endocrine Society ·doi:10.1210/jendso/bvag056

Adenomyosis is an intractable gynecological disorder that can give rise to severe pelvic pain, heavy menstrual bleeding, and infertility, predominantly affecting women of reproductive age. The limited efficacy of current pharmacological int…

case-report 2025
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.70140

Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo-ovarian fistulas associated with endometriosis, highlighting the potential for conservative management i…

article 2025
Fertility and Sterility ·doi:10.1016/j.fertnstert.2025.07.168
article 2025
Reproductive medicine and biology ·doi:10.1002/rmb2.12654

Purpose: This study evaluated whether embryo cryopreservation before surgery (ECBS) improves clinical outcomes in in vitro fertilization (IVF) patients with endometrioma. Methods: This retrospective study included patients aged 28-42 years …

article 2025
·doi:10.1093/humrep/deaf097.083

Abstract Study question What is the involvement of DNA double-strand breaks (DDSBs) signaling pathway in primordial follicle depletion in endometriosis and the role of melatonin in this pathway? Summary answer Endometriosis increases percen…

article 2025
BMC women's health ·doi:10.1186/s12905-025-03817-w

Adenomyosis often causes dysmenorrhea in women of reproductive age. Progestins such as levonorgestrel intrauterine system (LNG-IUS) are often used for treatment, but some patients experience progesterone resistance, showing poor treatment r…

article 2025
F&S science ·doi:10.1016/j.xfss.2025.06.002

OBJECTIVE: To compare the transcriptomes induced by estrogens used in combined oral contraceptives (COCs): estetrol (E4), ethinylestradiol (EE), and estradiol (E2) in human primary endometriotic stromal cells. DESIGN: mol/L) for 24 hours. T…

preprint 2023
·doi:10.21203/rs.3.rs-2834252/v1

Abstract Background Previous studies have shown the ovarian carcinoma after laparscopic cystectomy of endometrioma arises through the recurrence of endometrioma. Then it can be assumed that reduction of ovarian endometrioma recurrence throu…

article 2022
F&S science ·doi:10.1016/j.xfss.2022.04.004

Objective To evaluate the phosphorylation of estrogen receptor α at serine-118 (phospho-ERα S118) in the endometrium, ovarian endometrioma, and deep infiltrating endometriosis (DIE). Design Experimental study. Setting University-affiliated …

book-chapter 2022
·doi:10.1016/b978-0-323-90805-4.00004-3
article 2022
Scientific reports ·doi:10.1038/s41598-022-22413-8

The purpose of this study was to establish a novel mouse model of adenomyosis suitable for longitudinal and quantitative analyses and perinatal outcome studies. Using a 30 G needle, the entire uterine wall of one horn was mechanically punct…

preprint 2022
·doi:10.21203/rs.3.rs-1332354/v2
preprint 2022
·doi:10.21203/rs.3.rs-1332354/v1
other 2022
Biomedicines ·doi:10.3390/biomedicines10102627

The purpose of this study was to establish a new mouse model of endometriosis that mimics real-world women's health problems, in which women continue to be affected by endometriosis long before they wish to become pregnant, and to evaluate …

other 2021
Journal of reproductive immunology ·doi:10.1016/j.jri.2021.103371

OBJECTIVES: This study aimed to determine the systemic and local proportions, focal localization, and characteristics of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in endometriosis. STUDY DESIGN: Peripheral blood and pe…

article 2021
·doi:10.1016/j.jri.2021.103388
article 2018
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118806395
review 2018
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13559

Endometriosis is characterized by the implantation and growth of endometriotic tissues outside the uterus. It is widely accepted the theory that endometriosis is caused by the implantation of endometrial tissue from retrograde menstruation;…

article 2018
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13674

AIM: Adenomyosis is a common gynecological disorder that causes dysmenorrhea, hypermenorrhea and metrorrhagia. Previously, we reported that 24 weeks of dienogest treatment is highly effective for pain in symptomatic adenomyosis. Up to prese…

article 2018
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2018.04.021
other 2017
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.09.036

OBJECTIVES: To characterize peritoneal dendritic cells (DCs) in endometriosis and to clarify their role in its etiology. DESIGN: Experimental. SETTING: University hospital. PATIENT(S): Sixty-three women (35 patients with endometriosis an…

other 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.07.1077

OBJECTIVE: To determine the prevalence rate of subsequent development of ovarian cancer after excision of endometrioma. DESIGN: Retrospective cross-sectional study. SETTING: University hospital. PATIENT(S): A total of 485 women with endo…

article 2016
Journal of reproductive immunology ·doi:10.1016/j.jri.2016.12.002
article 2016
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-1515

CONTEXT: Endometriosis is an estrogen-dependent, chronic inflammatory disease. Recent studies have shown that vitamin D (VD) is an effective modulator of the immune system and plays an important role in controlling many inflammatory disease…