Xu C

BACKGROUND: Fibrosis, angiogenesis and chronic inflammation are the intrinsic characteristics of endometriosis. It is accompanied by significant changes in the cell composition of both ectopic and eutopic endometrial tissues, occurring both…

RESEARCH QUESTION: Do iron metabolism and ferroptosis influence oocyte and embryo quality in patients with endometriosis undergoing IVF/intracytoplasmic sperm injection (ICSI), or in a mouse model? DESIGN: Fifty-seven patients with laparos…

This study investigated fertility-related quality of life among married women of reproductive age (20-45 years) with endometriosis-associated infertility, focusing on the mediating role of family resilience between infertility-related stres…

Sleep deprivation (SD) is a significant risk factor for reproductive dysfunction. This review aims to synthesize evidence establishing that oxidative stress (OS) is the key pathological mediator of SD-induced reproductive impairments in bot…

Abstract Ferroptosis is linked to various diseases, but the role of transferrin (TF) in endometriosis (EM) remains unclear. Expression levels of ferroptosis-related proteins, including transferrin (TF), transferrin receptor (TFRC), and glut…

BackgroundThis study aims to evaluate the efficacy of a three-dimensional visualization operative planning system (3DVOPS) in ultrasound-guided percutaneous microwave ablation (US-PMWA) for the treatment of large uterine fibroids.MethodsFro…

While epidemiological studies have associated endometriosis with ovarian cancer risk, the causal relationships across anatomic subtypes and histotypes remain undefined. Using two-sample Mendelian randomization with 84 genetic instruments (F…

BackgroundWhile the phenotypic link between body mass index (BMI) and some female reproductive disorders is well established, the genetic architecture and causal relationships have not been systematically studied. We aimed to create an atla…

PurposeFor unexpected low-prognosis patients (Group 1 and Group 2) defined by POSEIDON criteria, how to maximize the live birth rate while controlling the multiple birth rate by tailoring the embryo transfer number and quality?MethodsThis w…

AimPolycystic ovary syndrome (PCOS) is a common endocrine disorder with high incidence. It has been reported that patients with PCOS are at great risk of developing endometrial cancer (EC). Our study was aimed to analyze the shared gene sig…

BackgroundBovine endometritis is a prevalent uterine disease that directly curtails reproductive performance and indirectly reduces milk production by increasing calving intervals. Postpartum uterine bacterial infection is the primary cause…

BACKGROUND: To investigate whether endometriosis is associated with the risk of incident nonalcoholic fatty liver disease (NAFLD). METHODS: Data were retrieved from Nurses' Health Study II with participants followed up from 1995 to 2017. A…

ObjectiveTo assess the efficacy of preimplantation genetic testing for aneuploidies (PGT-A) compared to intracytoplasmic sperm injection (ICSI) alone in couples undergoing ICSI treatment because of severe male infertility.DesignMulticentre,…

BackgroundPreimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) has been widely utilized to select euploid embryos in patients carrying balanced chromosomal rearrangements (BCRs) by chromosome copy number analys…

PurposeThis study aims to summarize and analyze the existing research on anxiety and depression within the field of assisted reproduction technology, exploring current hotspots, emerging frontiers, and trends, while offering insights for fu…

BackgroundDysmenorrhea, a common concern among female college students, is closely linked to anxiety and depression, particularly during the early menstrual phase (the first one to two days of menstruation), when cramping pain in the lower …

Ovarian cancer (OC) remains the most lethal gynecological malignancy, primarily due to its late-stage diagnosis, frequent recurrence, and resistance to conventional chemotherapy. A critical factor contributing to OC's aggressiveness is the …

PURPOSE: The study was designed to investigate whether estrogen regulates cell migration through cell polarity signaling and contributes to adenomyosis development. METHODS: In vitro study, Ishikawa cells received different treatments, Wes…

ObjectiveTo investigate the associations between triglyceride glucose-body mass index (TyG-BMI) and reproductive outcomes in women with polycystic ovary syndrome (PCOS) undergoing frozen embryo transfer (FET).MethodsThis retrospective cohor…

Ovarian development is a complex process, with early stages laying a crucial foundation for subsequent egg production. To better understand this developmental trajectory from early stages to the peak of egg production, this study employed t…

This study aims to examine the specific relationships between gut, oral, and vaginal microbiota and the frozen embryo transfer (FET) process. Patients undergoing fertility treatment who met the inclusion criteria were included in this study…

The human vascular system, comprising endothelial cells (ECs) and mural cells, covers a vast surface area in the body, providing a critical interface between blood and tissue environments. Functional differences exist across specific vascul…

BACKGROUND AND AIMS: The association of the triglyceride-glucose (TyG) index, a promising novel biomarker for insulin resistance, with the risk of endometriosis has not been investigated to date. This nationwide study aimed to explore the a…

OBJECTIVE: To present a new noninvasive technique for automatic diagnosis of adenomyosis, using a novel end-to-end unified network framework based on transformer networks. STUDY DESIGN: This is a prospective descriptive study conducted at …