OBJECTIVE: This study aimed to evaluate the effect of Omega-3 Fatty Acids (ω-3 PUFAs) on endometriosis. DESIGN: The authors conducted a comprehensive search of the PubMed, Embase, Cochrane Library and Web of Science databases, focusing exc…
BACKGROUND AND OBJECTIVE: Sepsis-related acute lung injury (S-ALI) had become an important public health issue worldwide. However, the mechanism of S-ALI was still not fully understood. This study aims to investigate the possibility of exos…
Identifying the ureters in patients with advanced endometriosis and severe pelvic adhesive disease can be challenging. Adhesiolysis along the deformed pelvic sidewall may increase the risk of prolonged operative time and incidental ureteral…
Leiomyomas (LM) and adenomyosis (AM) are common gynecological diseases with high incidence rates and an increasing trend of affecting younger women. Accurate detection and differentiation of LM and AM in ultrasound images are crucial for se…
The accumulation of regulatory T cells (Tregs) in the tumor microenvironment is a key factor for immunosuppression and immune escape of cancer cells. Genistein is a natural isoflavonoid in soybeans, possessing a wide range of pharmacologica…
BACKGROUND: Surgery is the primary treatment for Endometrial Stromal Sarcoma (ESS), however, a substantial proportion of patients with ESS experience recurrence or metastasis. Currently, surgery and local ablation are the main treatments fo…
Oral dysbiosis increases the risk of oral diseases and systemic diseases, with many related conditions overlapping with systemic diseases triggered by gut dysbiosis. Studies have shown that the oral cavity serves as an endogenous reservoir …
BACKGROUND: Endometriosis is an estrogen-dependent disorder with unclear molecular mechanisms. Ferroptosis, a regulated iron-dependent cell death, may play a key role, yet the specific genes involved remain underexplored. METHODS: Ferropto…
Intravenous leiomyomatosis (IVL) is a rare subtype of benign smooth muscle tumor that can exhibit malignant-like biological behavior. Originating in the uterus, IVL grows in mass-like formations within small veins and can extend into the in…
BACKGROUND: Comprehensive sonographic evaluation of pre- and postmenopausal women with abnormal uterine bleeding is essential for accurate diagnosis and the optimization of curative outcomes for endometrial malignancy. Microvascular flow im…
BACKGROUND: As the first discovered member of the neurotrophin family, nerve growth factor (NGF) plays fundamental roles in peripheral sensory and sympathetic neuronal development and survival. Recent evidence reveals its tumour-promoting e…
BACKGROUND: To compare in-vitro fertilization and embryo transfer (IVF-ET) pregnancy outcomes following endometrial polypectomy using either a manual mechanical hysteroscopic tissue resection device (mHTR) or traditional mechanical resectio…
To elucidate the mechanisms of endometriosis-associated infertility and identify potential drug targets by targeting PI3K/Akt and NF-κB signaling pathways. This study assessed clinical characteristics, inflammatory and oxidative stress biom…
OBJECTIVE: To evaluate the effectiveness of various medications for the treatment of endometriosis-related pain through a network meta-analysis. DATA SOURCES: A comprehensive search was conducted in PubMed, Embase, Web of Science, and the …
PURPOSE: Women with polycystic ovary syndrome (PCOS) show greater heterogeneity in ovarian responses during ovarian stimulation. We aimed to investigate the potential predicting factors among individualized basic parameters that affect poor…
BACKGROUND: Sexually transmitted infections (STIs) are a global public health issue, due to their high prevalence and potential impact on pregnancy outcome and fetal health. The objective of this study is to investigate the prevalence of ST…
Primary squamous cell carcinoma (SCC) of the myometrium associated with adenomyosis is exceedingly rare. We present a case involving a 49-year-old female patient who experienced irregular menstruation for 3 months and was initially misdiagn…
Early screening and diagnosis, precise treatment and prognosis prediction are pivotal for enhancing cancer patients' survival rates and for improving their life quality, it is the same case in gynecological malignancies. Among gynecological…
BACKGROUND: Gynecological diseases significantly impact the reproductive health in women of childbearing age (WCBA). However, there is currently a lack of analysis on the specific burden and forecast of common gynecological diseases for thi…
BACKGROUND: The main characteristics of the robotic surgical system include high-definition three-dimensional imaging, flexible and stable instruments, and an ergonomic console design. Incorporating robotic systems with laparoendoscopic sin…
BACKGROUND: Oxidative stress and metabolic disorders significantly contribute to the development of polycystic ovarian syndrome (PCOS). Heme oxygenase-1 (HMOX1) plays a key role in the degradation of heme and the regulation of oxidative str…
BACKGROUND: Glycolysis, a classic characteristic of cancer cells, can drive cancer progression by generating lactate, which play as a key immunosuppressive mediator. Currently, ubiquitin-specific proteases 5 (USP5) has been demonstrated to …
BACKGROUND: Cholangiocarcinoma is a common hepatic malignant tumor with an unfavorable prognosis. Therefore, we systematically evaluated the transcriptomic landscape of CHOL by whole transcriptome sequencing technology in this study and con…
Adenomatoid tumors are rare, specific, benign tumors of the reproductive tract that originate from mesenchymal tissue. A patient was diagnosed with uterine fibroids 1 year previously when a mass of approximately 30 mm was found in the left …
Low-grade serous ovarian carcinoma (LGSOC) is a rare subtype of ovarian cancer that accounts for approximately 6% to 10% of serous ovarian cancers. The clinical treatment of LGSOC is similar to that of high-grade serous ovarian carcinoma, h…