Ashok Agarwal

review 2005

Oxidative stress and its implications in female infertility - a clinician's perspective

Reproductive biomedicine online ·doi:10.1016/s1472-6483(10)61174-1

Reactive oxygen species (ROS) have a role in the modulation of gamete quality and gamete interaction. Generation of ROS is inherent in spermatozoa and contaminating leukocytes. ROS influence spermatozoa, oocytes, embryos and their environme…

article 2005

Peritoneal fluid leptin is associated with chronic pelvic pain but not infertility in endometriosis patients*

Human Reproduction ·doi:10.1093/humrep/dei376

BACKGROUND: Leptin influences the proinflammatory immune responses and has angiogenic activity in vitro and in vivo. The objective of this study was to evaluate the peritoneal fluid levels of leptin in patients with endometriosis and idiopa…

article 2005

Relationship of Peritoneal Fluid Oxidative Stress Status and Subsequent Pregnancy in Endometriosis Patients

·doi:10.1016/j.fertnstert.2005.07.302

article 2005

Role of Endometriosis on Oocyte Quality and Fertility Outcome—An Evidence Based Review

·doi:10.1016/j.fertnstert.2005.07.1127

review 2005

Role of oxidative stress in female reproduction

Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-3-28

In a healthy body, ROS (reactive oxygen species) and antioxidants remain in balance. When the balance is disrupted towards an overabundance of ROS, oxidative stress (OS) occurs. OS influences the entire reproductive lifespan of a woman and …

article 2004

Effect of immunomodulatory agent − pentoxifylline on in vitro blastocyst development rate

·doi:10.1016/j.fertnstert.2004.07.839

article 2004

Reversibility of tumor necrosis factor (TNF)-α induced toxic effects by infliximab in human spermatozoa

·doi:10.1016/j.fertnstert.2004.07.408

review 2004

Role of free radicals in female reproductive diseases and assisted reproduction

Reproductive biomedicine online ·doi:10.1016/s1472-6483(10)62151-7

Infertility is a common problem experienced by many couples. Numerous treatments are available for female infertility. However, in some cases, the treatment is empirical in nature because the aetiology of infertility is not fully understood…

other 2004

Role of reactive oxygen species in gynecologic diseases

Reproductive medicine and biology ·doi:10.1111/j.1447-0578.2004.00068.x

Free radicals derived from molecular oxygen and nitrogen are highly reactive metabolites called reactive oxygen species (ROS). Cells continuously produce free radicals and ROS as part of the metabolic process. They are involved in the vario…

article 2004

TNF-alpha induced embryotoxicity and role of TNF-alpha blocker-infliximab on blastocyst development rate

·doi:10.1016/j.fertnstert.2004.07.413

article 2004

Toxicity of tumor necrosis factor (TNF)-α on human spermatozoa − Possible role in endometriosis associated infertility

·doi:10.1016/j.fertnstert.2004.07.407

article 2003

Assessment of the predictive value of follicular fluid IL-6 in IVF cycles

·doi:10.1016/s0015-0282(03)02057-0

article 2003

Differential contribution of reactive oxygen species and tumor necrosis factor-α to the peritoneal fluid-induced embryotoxicity in endometriosis patients

·doi:10.1016/s0015-0282(03)01517-6

article 2003

Effect of TNF-α blocker (Infliximab) on blastocyst development rate

·doi:10.1016/s0015-0282(03)01368-2

article 2003

Effects of peritoneal fluid from endometriosis patients on pre-implantation mouse embryo development and apoptosis

·doi:10.1016/s0015-0282(03)01516-4

review 2003

Role of reactive oxygen species in the pathophysiology of human reproduction

Fertility and Sterility ·doi:10.1016/s0015-0282(02)04948-8

OBJECTIVE: To summarize the role of reactive oxygen species (ROS) in the pathophysiology of human reproduction. DESIGN: Review of literature. SETTING: Fertility research center and obstetrics and gynecology department in a tertiary care f…

article 2002

Assessment of leptin levels in the peritoneal fluid of patients with pelvic endometriosis and idiopathic infertility

·doi:10.1016/s0015-0282(02)04062-1

article 2002

Assessment of the predictive value of follicular fluid cytokines and reactive oxygen species in IVF cycles

·doi:10.1016/s0015-0282(02)03392-7

article 2002

Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trial

·doi:10.1016/s0015-0282(01)03024-2

article 2001

Superovulation and Intrauterine Insemination in Cases of Treated Mild Pelvic Disease

Journal of assisted reproduction and genetics ·doi:10.1023/a:1026446612485

article 2001

The effect of follicular fluid reactive oxygen species on the outcome of in vitro fertilization.

International journal of fertility and women's medicine

OBJECTIVE: To examine the presence of reactive oxygen species (ROS) in the follicular fluid of women undergoing in vitro fertilization (IVF) and identify its role in pregnancy outcome. STUDY DESIGN: In this prospective study, ROS and total …

article 2000

Effect of Peritoneal Fluid of Infertile Mild/Minimal Endometriosis and Idiopathic Infertility Patients on In Vitro Mouse Embryo Development

·doi:10.1016/s0015-0282(00)01263-2

article 1999

Effect of peritoneal fluid from endometriosis patients on sperm motion characteristics and acrosome reaction.

International journal of fertility and women's medicine

OBJECTIVE: To determine whether peritoneal fluid from women with endometriosis contributes to infertility by impairing sperm motion and functional characteristics. METHODS: Women with endometriosis (n = 20) underwent laparoscopy for inferti…

article 1997

Importance portance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility

Fertility and Sterility ·doi:10.1016/s0015-0282(97)00343-9

OBJECTIVE: To determine whether reactive oxygen species in peritoneal fluid might be a factor in infertility. DESIGN: Prospective study. SETTING: Andrology laboratory and gynecology clinic at a tertiary care facility. PATIENT(S): Women with…

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