OBJECTIVE: The purpose of this study was to investigate the effect of gonadotropin dose and endometrial thickness (EMT) on pregnancy outcome in patients undergoing intrauterine insemination (IUI). METHODS: We retrospectively analyzed data …
BACKGROUND: With the improvement of bacterial detection, the theory of the sterile female upper reproductive tract has been frequently challenged in recent years. However, thus far, no researchers have used ovaries as study targets. METHOD…
BACKGROUND: Myopia is one of most common eye diseases in the world and affects 1 in 4 Americans. It is a complex disease caused by both environmental and genetics effects; the genetics effects are still not well understood. In this study, w…
Objective To provide novel insights into the clinical treatment of adenomyosis. Methods Two hundred patients with adenomyosis were enrolled in this prospective, nonrandomized, parallel-controlled study with a 1-year follow-up in our hospita…
BACKGROUND: CA125 is a prevalently used serum biomarker for detecting ovarian cancer over the last three decades. However, it has a significant deficiency in screening for early-stage cancer. With the purpose of exploring an effective appro…
Histone modifications of lysine residues have been implicated as having diagnostic and/or prognostic significance in numerous types of cancer. In the present study, the significance of the histone H3 methylation of lysine 4 (H3K4) and lysin…
This work investigated the role of paired box 2 (PAX2) in endometrial cancer and its epigenetic regulation mechanism. Endometrial cancer tissues and cell lines exhibited increased PAX2 expression compared with hyperplasia, normal endometriu…
We evaluated the diagnostic value of hepatocyte nuclear factor 1 beta (HNF-1β) and napsin A for diagnosing ovarian clear cell carcinoma. Immunohistochemical EnVision was used to measure HNF-1β and napsin A expression in 38 cases of ovarian …
BACKGROUND: Endometriosis is characterized by the presence of tissue that is morphologically and biologically similar to normal endometrium in locations outside the uterus. Surgical and hormonal treatment of endometriosis have unpleasant si…
AIM To study the effect of Shaofu Zhuyu Pill(Angelicae sinensis Radix,Paeoniae Radix rubra,Chuanxiong Rhizoma,etc.)(SZP) on the expression level of MMP-9 and TIMP-1 mRNA in endometriosis(EMS) rats.METHODS The model of EMS rats was made by i…
Objective To investigate the influences of Shaofu Zhuyu Wan on expressions of endometrial tumor necrosis factor-α(TNF-α) and vascular endothelial growth factor(VEGF) mRNA in rats with endometriosis.Methods The rat model of endometriosis was…
Objective: To investigate the possible mechanism of Dan'e Fukang decocted extract(DFD) on pelvic pain of endometriosis(EMS) rats.Methods: The EMS rats were made by implanted tunica intima method.Then rats were randomly divided into 5 groups…
Objective:To find out the diagnostic value of ultrasonography to endometriosis.Methods:To retrospectively analyse the results of ultrasonography of 90 cases who were finally diagnosed by laparoscopy before operation.And compare ultrasonogra…