Zeng X

BACKGROUND: Patients undergoing assisted reproductive technology (ART) frequently manifest sleep disturbances and psychological morbidity. This study examined associations between cerebral activation patterns, sleep quality, and psychologic…

RESEARCH QUESTION: Is there a relationship between the location of adenomyosis lesions and obstetric and neonatal outcomes? DESIGN: A total of 466 women diagnosed with adenomyosis via transvaginal ultrasound between January 2019 and Decemb…

BackgroundNumerous studies have suggested that assessing endometrial and subendometrial blood flow can contribute to the evaluation of endometrial receptivity. However, there remains a lack of unified expert consensus regarding the assessme…

OBJECTIVES: This study aimed to comprehensively examine coagulation parameters in patients with endometriosis versus those without to determine hematologic alterations associated with endometriosis. METHODS: Embase, PubMed, CINAHL, Web of S…

As a major global health threat, tumors present significant clinical challenges due to their heterogeneity, metastatic potential, and therapy resistance. In recent years, non-coding RNAs, particularly microRNAs (miRNAs), have emerged as cru…

YAP1 (Yes-associated protein 1), a central downstream effector of the Hippo signaling pathway, is tightly regulated through coordinated post-transcriptional and post-translational mechanisms. At the post-transcriptional level, expression st…

IntroductionOvarian cancer (OC) and endometrial cancer (EC) represent two prevalent tumors within the female reproductive system, characterized by high incidence rates. Nonetheless, the clinicopathological features of synchronous endometria…

BackgroundUnexplained recurrent pregnancy loss (uRPL), defined as the loss of two or more pregnancies without an identified cause, affects approximately 1-2% of women trying to conceive. Emerging evidence suggests that an imbalance in mater…

Background and objectivesOligomenorrhea and hypomenorrhea were common conditions in outpatient visit which affected child-bearing aged women, and the conventional progesterone treatment has been related to several side effect and contradict…

ObjectiveOvarian cancer (OC) is a common malignant tumor in women, with poor prognosis and high mortality rates. Early diagnosis, screening, and prognostic prediction of OC have long been focal points and challenges in this field. In recent…

IntroductionMetabolic syndrome is a serious public health concern across the globe. However, the typical metabolites and mechanisms underlying the decreased fertility related to metabolic syndrome is still elusive.ObjectivesThe aim of the p…

Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse fetal outcomes, including fetal morbidity and mortality. It is a complex liver disorder influenced by genetic interactions, estrogen levels, and env…

BackgroundOvarian dysfunction caused by aging restricts female reproductive capacity and causes age-related health problems. Ferroptosis is an important mode of cell death during accelerated aging. Oviductus Ranae (OR), a traditional Chines…

Objective To identify novel and noninvasive biomarkers for the diagnosis of adenomyosis and to provide potential therapeutic targets. Design We conducted a cross-sectional study using data from 110 women of reproductive age who underwent pe…

ObjectivesThe study was designed to investigate the correlation between body mass index (BMI) along with both ovulation effect and clinical pregnancy rate in patients with polycystic ovary syndrome (PCOS), as well as to analyze the factors …

IntroductionProgestin, commonly used in oral contraception and preventing preterm birth, elicits various off-target side effects on brain and gastrointestinal (GI) functions, yet the precise mechanisms remain elusive. This study aims to pro…

Background and aimsHepatic fibrosis (HF) is a critical step in the progression of hepatocellular carcinoma (HCC). Gene associated with retinoid-IFN-induced mortality 19 (GRIM19), an essential component of mitochondrial respiratory chain com…

Mitochondria play a crucial role in maintaining the normal physiological state of cells. Hence, ensuring mitochondrial quality control is imperative for the prevention and treatment of numerous diseases. Previous reviews on this topic have …

Non-persistent endocrine-disrupting chemicals (EDCs) are of significant concern due to their reproductive toxicity. Previous research reported a relationship between a single type of EDCs and endometriosis. Yet, evidence regarding mixed exp…

BackgroundThe proliferation of porcine ovarian granulosa cells (GCs) is essential to follicular development and the ubiquitin-proteasome system is necessary for maintaining cell cycle homeostasis. Previous studies found that the deubiquitin…

Upper ureteral stricture is a relatively rare but increasingly encountered condition in clinical practice. While simple stricture can often be addressed through endoluminal treatment or surgical reconstruction, complex upper ureteral strict…

PURPOSE: To examine the associations between use of statins and risks of various ovarian, uterine, and cervical diseases, including ovarian cancer, endometrial cancer, cervical cancer, ovarian cyst, polycystic ovarian syndrome, endometriosi…

Systemic lupus erythematosus (SLE), a prevalent autoimmune disease predominantly affecting women of childbearing age, presents ongoing challenges despite notable advances in diagnosis and treatment. Although survival rates for SLE patients …

ObjectivesTo systematically assess the associations between various immune-mediated diseases (IMDs) and human papillomavirus (HPV)-associated diseases.DesignRetrospective cohort study.SettingUK Biobank.ParticipantsA total of 500 371 subject…

PurposeWe aimed to compare the DNA methylation profiles of human embryos cultured in uninterrupted or interrupted incubators.MethodsThis study included 9 women, ≤ 30 years old (range: 20-30 years), without a history of genetic diseases or s…