Saito K

No ORCID on file · 21 papers in corpus · active 2003-2025

Study types

  • article 6
  • other 2
  • case-report 1
  • review 1

Condition tags

  • endometriosis 9
  • infertility 1
  • thoracic_endometriosis 1
  • adenomyosis 1
  • bladder_endometriosis 1
article 2025
Reproduction (Cambridge, England) ·doi:10.1530/rep-25-0132

IN BRIEF: By tissue-selective next-generation sequencing, we showed that adenomyotic epithelium harbored genomic alterations thought to be relevant to the development and progression of adenomyosis, including somatic mutations in several ca…

2025
Tissue barriers ·doi:10.1080/21688370.2024.2361976

The bicellular tight junction molecule cingulin (CGN) binds to microtubules in centrosomes. Furthermore, CGN contributes to the tricellular tight junction (tTJ) proteins lipolysis-stimulated lipoprotein receptor (LSR) and tricellulin (TRIC)…

2024
Mammalian genome : official journal of the International Mammalian Genome Society ·doi:10.1007/s00335-024-10063-2

Mammalian genome research has conventionally involved mice and rats as model organisms for humans. Given the recent advances in life science research, to understand complex and higher-order biological phenomena and to elucidate pathologies …

other 2024
Tissue barriers ·doi:10.1080/21688370.2024.2304443

It is known that there are abnormalities of tight junction functions, cell migration and mitochondrial metabolism in human endometriosis and endometrial carcinoma. In this study, we investigated the effects of growth factors and their inhib…

article 2023
Cancers ·doi:10.3390/cancers15235635

Endometriosis is known to be associated with an increased risk of endometrioid and clear cell ovarian cancer. However, the association between endometriosis and endometrial cancer is controversial. Therefore, we retrospectively analyzed the…

2023
Tissue barriers ·doi:10.1080/21688370.2022.2106113

Lipolysis-stimulated lipoprotein receptor (LSR), a lipid metabolism-related factor localized in tricellular tight junctions (tTJs), plays an important role in maintaining the epithelial barrier. LSR is highly expressed in well-differentiate…

2022
Patient safety in surgery ·doi:10.1186/s13037-022-00328-7

BackgroundIn Japan, dilatation & curettage (D&C) has been performed under general anesthesia as a surgery for an early pregnancy miscarriage for a long time. In 2016, manual vacuum aspiration (MVA) under general anesthesia was introduced at…

2022
Nature communications ·doi:10.1038/s41467-022-28568-2

It has become evident that somatic mutations in cancer-associated genes accumulate in the normal endometrium, but spatiotemporal understanding of the evolution and expansion of mutant clones is limited. To elucidate the timing and mechanism…

2021
Reproductive medicine and biology ·doi:10.1002/rmb2.12397

PurposeWe investigated the cumulative live birth rate (CLBR) in women receiving governmental subsidies for assisted reproductive technology (ART) in Saitama Prefecture, Japan.MethodsWomen who applied for subsidies from Saitama Prefectural G…

review 2021
Cancers ·doi:10.3390/cancers13246341

Tight junction proteins play roles beyond permeability barriers functions and control cell proliferation and differentiation. The relation between tight junctions and the signal transduction pathways affects cell growth, invasion and migrat…

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00230-6

Claudin-2 (CLDN-2) is a leaky-type tight junction protein, and its overexpression increases tumorigenesis of some types of cancer cells. In the present study, to examine the possibility of targeting CLDN-2 in the therapy for endometrioid en…

2020
BMC pregnancy and childbirth ·doi:10.1186/s12884-020-03362-4

BackgroundThe World Health Organization does not recommend dilatation and sharp curettage (D&C) for the surgical treatment of miscarriage during the first trimester because this may cause Asherman's syndrome due to endometrial damage; there…

2019
International journal of molecular sciences ·doi:10.3390/ijms20040899

Background: Vanin-1 is a novel acute kidney injury (AKI) biomarker that has not been clinically investigated as a biomarker for obstructive nephropathy. This study investigated the diagnostic value of vanin-1 as a biomarker for adult obstru…

2019
Scientific reports ·doi:10.1038/s41598-019-38724-2

Previous studies suggested ovarian stimulation was associated with lower birth weight and higher risk of preterm delivery (PTD) from fresh embryo transfers (ETs). However, whether the increased risk differs between distinct ovarian stimulat…

article 2018
Acta radiologica open ·doi:10.1177/2058460118801164

Intrathoracic endometriosis is classified into pleurodiaphragmatic endometriosis and bronchopulmonary endometriosis. Bronchopulmonary endometriosis is rare. Computed tomography (CT) findings of bronchopulmonary endometriosis are lung nodule…

2017
BMC pregnancy and childbirth ·doi:10.1186/s12884-017-1294-8

BackgroundEctopic pregnancy (EP) occurs in 1% of pregnancies and is reported to be more common in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) pregnancies. An abdominal ectopic pregnancy (AEP) is a rare form of EP, and…

2017
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-017-0869-7

PurposeThis study aimed to clarify the risks of adverse pregnancy outcomes in patients who conceive singletons after frozen embryo transfer (FET) during a hormone replacement cycle and their offspring.MethodsA retrospective cohort study was…

case-report 2012
Hinyokika kiyo. Acta urologica Japonica

We report a case of vesical endometriosis that worsened during the early pregnancy period. A 37-year old woman had been under treatment for endometriosis (including vesical endometriosis) by a gynecologist during the past 10 years. She was …

article 2011
Kyobu geka. The Japanese journal of thoracic surgery

We reported a case of catamenial pneumothorax caused by diaphragmatic endometriosis that was histologically confirmed. A 49-year-old female who had recurrent chest pain and cough appearing on the day preceding each menstruation from 5 years…

article 2007
Surgery today ·doi:10.1007/s00595-006-3440-1

Endometriosis is a relatively common disorder in women of reproductive age; however, appendiceal endometriosis is rare. Thus, a definitive diagnosis is likely to be established only by histology of the appendix. We report a case of endometr…

article 2003
Molecular and cellular endocrinology ·doi:10.1016/s0303-7207(03)00083-2

We investigated the relationship between interleukin-6 (IL-6) levels and subset profiles of T lymphocyte (T-cell) and macrophage in peritoneal fluid (PF) with or without endometriosis (EM). IL-6 levels in PF with EM were significantly highe…