Luigi Cobellis

Objective This preliminary study sought to provide initial insights into lead concentrations within the follicular fluid of infertile patients with and without endometriosis, tentatively observing any potential links between lead presence a…

BACKGROUND: To date, there are no clear guidelines available on the treatment of adenomyosis-associated pelvic pain (AAPP); however, numerous hormonal treatments (HTs) are currently being used off-label. We conducted a systematic review and…

BACKGROUND: Hormone pre-treatment is still used before assisted reproductive technique (ART) in endometriotic women, but evidence supporting this recommendation is conflicting. OBJECTIVES: To evaluate whether hormone pre-treatment with gona…

BACKGROUND: Accurate reporting of participants' race and ethnicity is essential for assessing the representativeness of study populations and for identifying potential disparities in diagnosis, treatment, and outcomes. OBJECTIVES: To asses…

Women with endometriosis were deemed more prone to COVID-19 infection in some reports. Considering that endometriosis-related aberrant immune response, understanding how COVID-19 vaccination influences its clinical status is crucial. The ai…

Despite laparoscopy being a standardized option to diagnose pelvic endometriotic implants, non-invasive biomarkers are necessary to avoid the discomfort of invasive procedures. Recent evidence suggests a potential role of microRNAs (miRNAs)…

BACKGROUND: Laparoscopic excision of endometrioma and subsequent hemostasis have detrimental effects on ovarian reserve. OBJECTIVES: To evaluate which hemostatic approach after stripping cystectomy shows less damage on ovarian reserve. SE…

BACKGROUND: Ion channels play a crucial role in many physiological processes. Several subtypes are expressed in the endometrium. Endometriosis is strictly correlated to estrogens and it is evident that expression and functionality of differ…

Scopo dello studio. Valutazione della relazione tra dolore ed endometriosi, ed in particolare la possibile correlazione tra disturbi vescico-urinari e la quantita di fibre nervose e cellule gangliari resecate con l’intervento chirurgico lap…

È stato ipotizzato che un’alterazione dell’angiogenesi possa essere responsabile dei difetti di impianto in alcune condizioni di sterilità primaria ed associata ad endometriosi. VEGF e Notch sono molecole che partecipano in maniera rilevant…

Il dolore pelvico cronico è un’entità complessa, la cui natura è tuttora enigmatica e per il quale esistono poche strategie terapeutiche universalmente efficaci. L’endometriosi è una patologia ginecologica, cronica e benigna, importante cau…

Endometriosis is a chronic disease characterized by the presence of ectopic endometrial tissue outside of the uterus with mixed traits of benign and malignant pathology. In this study we analyzed in endometrial and endometriotic tissues the…

OBJECTIVE: To evaluate serum and peritoneal fluid concentrations of interferon-gamma-inducible protein-10 (CXCL10), a chemokine involved in local immune function, in women with endometriosis. DESIGN: Prospective study. SETTING: Division o…

A sensitive HPLC method with fluorescence detection was developed for the determination of bisphenol A (BPA) and bisphenol B (BPB) in human blood serum. The detection limits of the method were 0.18 and 0.20 ng/mL for BPA and BPB, respective…