Amparo Faus

Abstract STUDY QUESTION Could the miRNA cargo of extracellular vesicles (EVs) secreted by eutopic endometrium from women with endometriosis be involved in the pregnancy complications related to endometriosis? SUMMARY ANSWER EVs secreted by …

Abstract Study question Is the cargo of extracellular vesicles (EVs) secreted by the eutopic endometrium of women with endometriosis associated with their fertility problems? Summary answer EVs secreted by the eutopic endometrium of endomet…

Abstract Study question Does insulin resistance affect the immune-inflammatory status in infertile women with adenomyosis? Summary answer Insulin resistance worsens endometrial inflammation, disrupting immune cell recruitment and stromal pr…

BACKGROUND: Women with adenomyosis are characterized by having defective decidualization, impaired endometrial receptivity and/or embryo-maternal communication, and implantation failure. However, the molecular mechanisms underlying adenomyo…

Abstract Study question Is there any molecular deregulation in the gestational endometrium of women with adenomyosis responsible for adenomyosis-related pregnancy disorders? Summary answer Women with adenomyosis show deregulated molecular m…

Adenomyosis is related to infertility and miscarriages, but so far there are no robust in vitro models that reproduce its pathological features to study the molecular mechanisms involved in this disease. Endometrial organoids are in vitro 3…

The endometrium is recognized for its remarkable regenerative and remodeling capacity. Every month this hormonally regulated organ undergoes cycles of growth (from 0.5-2 to 7 mm), regression and shedding of two-third of the tissue, leading …

Endometrial regeneration is mediated, at least in part, by the existence of a specialized somatic stem cell (SSC) population recently identified by several groups using the side population (SP) technique. We previously demonstrated that end…