Juan Gilés
ORCID: 0000-0001-9666-970X
· 12 papers in corpus
article
2025
article
2025
Abstract Study question Does insulin resistance affect the immune-inflammatory status in infertile women with adenomyosis? Summary answer Insulin resistance worsens endometrial inflammation, disrupting immune cell recruitment and stromal pr…
article
2025
article
2024
BACKGROUND: Women with adenomyosis are characterized by having defective decidualization, impaired endometrial receptivity and/or embryo-maternal communication, and implantation failure. However, the molecular mechanisms underlying adenomyo…
article
2023
Abstract Study question Is there any molecular deregulation in the gestational endometrium of women with adenomyosis responsible for adenomyosis-related pregnancy disorders? Summary answer Women with adenomyosis show deregulated molecular m…
article
2023
Abstract Study question Do patients with adenomyosis have an impaired inflammatory state of the endometrium that could affect implantation and pregnancy? Summary answer Adenomyosis patients show increased proinflammatory cytokines expressio…
article
2022
Adenomyosis is related to infertility and miscarriages, but so far there are no robust in vitro models that reproduce its pathological features to study the molecular mechanisms involved in this disease. Endometrial organoids are in vitro 3…
article
2022
RESEARCH QUESTION: Do extracellular vesicles secreted by the endometrium of women with adenomyosis contain miRNAs involved in adenomyosis-related infertility? DESIGN: A descriptive study using organoids from eutopic endometrium of women wi…
article
2021
STUDY QUESTION: Is there a relationship between serum and endometrial progesterone (P4) levels, including P4 and metabolites (oestrone, oestradiol and 17α-hydroxyprogesterone), and endometrial receptivity? SUMMARY ANSWER: Serum P4 levels we…
article
2021
Research questionHow does the number of oocytes used affect the cumulative live birth rate (CLBR) in endometriosis patients who had their oocytes vitrified for fertility preservation?DesignRetrospective observational study including data fr…
article
2020
ObjectiveTo describe the outcome of fertility preservation (FP) using vitrified oocytes in patients with endometriosis and to determine the impact of ovarian surgery.DesignRetrospective observational study.SettingUniversity-affiliated priva…
article
2004
ObjectiveTo investigate whether conservative surgery on ovarian endometriomas before an IVF cycle improves fertility outcomes.DesignRetrospective, matched case-control study.SettingTwo academic IVF programs.Patient(s)One hundred eighty-nine…