J.L.H. Evers

Summary‘IT has been casually assumed that the classic association in the uterus itself of cyclic endometrial breakdown and bleeding also no doubt occurs in similar but ectopic endometrial fragments, and that such miniature menses into blind…

ObjectivesTo investigate whether the aminoterminal propeptides of type III procollagen are increased in patients with early endometriosis and to demonstrate that the subtle lesion of endometriosis is an active stage of the disease.DesignAmi…

Oestrogen receptors (ER) and progesterone receptors (PR) were measured in the rabbit model of endometriosis in eutopic and ectopic endometrium of pregnant animals (n = 7) and controls (n = 7). Immunostaining of cryostat sections of ectopic …

Endometriosis may be either symptomatic or asymptomatic. Recurrence rates are mostly calculated on the basis of symptomatic patients re-presenting to their doctor. Based on the number of patients who experience recurrence of symptoms after …

STUDY OBJECTIVE: To study the isolated influence of peritoneal endometrial implants on fertility in an adhesion-free rabbit model. STUDY DESIGN: Thirty-two rabbits with endometrium implants were used; 31 rabbits with fat implants served as…

The reasons for sub-fertility in patients with mild endometriosis remain unclear. Peritoneal fluid constituents may alter tubal transport and embryonic cleavage, with subsequent implantation disturbances. We used an animal model to study th…

In 25 rabbits (Group E) endometrium from the right uterine horn was transplanted onto the peritoneum. In 25 rabbits (Group C) fat was transplanted. After a recovery period of 12 weeks the does were mated, and killed 24 h later. In Group E t…

A decreased intraabdominal fibrinolytic activity has been proposed as an etiological factor in the development of endometriosis. To test this hypothesis plasminogen, fibrinogen, alpha 2-antiplasmin, alpha 2-macroglobulin, plasminogen activa…

Peritoneal fluid was collected in the periovulatory phase of the cycle from 25 women undergoing laparoscopy. Endometriosis was diagnosed in 13 patients (AFS score 1, N = 9; AFS score 2, N = 4) and 12 patients without endometriosis served as…

Peritoneal fluid volume was determined and concentrations of C-reactive protein, alpha 1-antitrypsin, acid-alpha 1-glycoprotein, alpha 2-macroglobulin, haptoglobin, complement factors C3 and C4, IgG, IgA and IgM were measured in the superna…

Endometriosis has an adverse effect on fertility. In severe endometriosis adhesions interfere with ovulation and tubal function. The mechanism by which mild endometriosis causes infertility remains unclear. We studied the effects of endomet…

Disruption of the BM can be found in metastasizing neoplasms. It has been suggested that also in some patients with endometriosis the BM is lacking, depending on the severity of disease. Thus studying the aspect of the BM would enable chara…

Endometriosis has an adverse effect on fertility. In severe endometriosis adhesions interfere with ovulation and tubal function. The mechanism by which mild endometriosis causes infertility remains unclear. We studied the effects of endomet…

Some authors have evaluated the efficacy of medical treatment for endometriosis by SLL at termination of therapy. The appearance of endometriotic lesions depends on ovarian activity. We studied the appearance of endometriotic lesions at SLL…

Failure of reconstructive tubal surgery is usually attributed to pre-existing endosalpingeal damage, recurrent adhesion formation or progressive inflammatory disease. We studied ovarian follicle development and ovulation by ultrasound in 25…