Is there a solution for recurrent endometriosis?
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Recurrence rates of endometriosis, often calculated from symptomatic patients, can reach 45% within five years, but the cause of symptoms, whether true recurrence or microscopic implant expansion, remains unclear.
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Abstract
Endometriosis may be either symptomatic or asymptomatic. Recurrence rates are mostly calculated on the basis of symptomatic patients re-presenting to their doctor. Based on the number of patients who experience recurrence of symptoms after medical or surgical therapy, recurrence rates of up to 45% after five years have been calculated. Whether the symptoms are due to real recurrence of disease or expanding, previously microscopic, endometriotic implants has not yet been established. Therapy should be tailored to the patient's complaints, but does not necessarily have to differ from that in patients with primary disease.
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Cited by (33)
- Progesterone Actions and Resistance in Gynecological Disorders 2022
- Efficacy of niclosamide on the intra‐abdominal inflammatory environment in endometriosis 2021
- Dienogest reduces endometrioma volume and endometriosis-related pain symptoms 2021
- Potential Therapeutic Options and Perspectives for Alleviation of Endometrial Estrogen Dominance and Progesterone Resistance in Endometriosis 2021
- Niclosamide suppresses macrophage-induced inflammation in endometriosis† 2020
- Endometriotic inflammatory microenvironment induced by macrophages can be targeted by niclosamide† 2018
- Use of Dienogest or Gonadotropin Releasing Hormone Agonist with Add back Hormone Therapy in Longterm Endometriosis Medical Management 2018
- Long-term medical management of endometriosis with dienogest and with a gonadotropin-releasing hormone agonist and add-back hormone therapy 2017
- Niclosamide As a Potential Nonsteroidal Therapy for Endometriosis That Preserves Reproductive Function in an Experimental Mouse Model 2016
- Combination use of ferulic acid, ligustrazine and tetrahydropalmatine inhibits the growth of ectopic endometrial tissue: A multi-target therapy for endometriosis rats 2014
- The elusive and controversial roles of estrogen and progesterone receptors in human endometriosis. 2014
- Recurrence of ovarian endometrioma after laparoscopic excision: Risk factors and prevention 2013
- Effect of Long-Term Use of Hormones on Endometriomas 2013
- Role of Surgery in Endometriosis-Associated Subfertility 2013
- Clinical applications of levonorgestrel-releasing intrauterine system to gynecologic diseases 2013
- Recurrence of endometrioma after laparoscopic excision and its prevention by medical management 2012
- Medical management of endometriosis 2012
- Prise en charge diagnostique et thérapeutique de l'endométriose par les médecins généralistes de Seine-Maritime 2012
- Long‐term adjuvant therapy for the prevention of postoperative endometrioma recurrence: a systematic review and meta‐analysis 2012
- Risk Factors for Endometriosis in a German Case–Control Study 2011
- The outcomes of repeat surgery for recurrent symptomatic endometriosis 2010
- Post-operative endometriosis recurrence: a plea for prevention based on pathogenetic, epidemiological and clinical evidence 2010
- 'Waiting for Godot': a commonsense approach to the medical treatment of endometriosis 2010
- Endometriosis research: animal models for the study of a complex disease 2010
- The effect of second‐line surgery on reproductive performance of women with recurrent endometriosis: A systematic review 2009
- Prise en charge d'une endométriose douloureuse 2007
- The medical management of endometriosis 2002
- Review of pain associated with minimal endometriosis. 2000
- Mapping the source and character of pain due to endometriosis by patient-assisted laparoscopy 1998
- Progestins for symptomatic endometriosis: a critical analysis of the evidence 1997
- Can hormone replacement therapy be used during medical therapy of endometriosis? 1994
- 1 Is endometriosis a disease? 1993
- 7 Endometriosis and pelvic pain 1993
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