J. A. Land

Since not all problems in endometriosis can be studied in the human, there is need of an animal model. We transplanted endometrial tissue of the rabbit into the peritoneal cavity and studied the changes after 12 weeks. At that time the endo…

Previous studies have investigated the role of Toll-like receptor (TLR)2 and TLR4 in susceptibility to and severity of Chlamydia trachomatis infections. In this study we employ a unique integrated approach to study the role of the intracell…

Reproductive research benefits from combining animal and clinical studies. In Leuven, rabbits have constituted an animal model for many reproductive disorders, especially for those that involved surgical treatment. Much of what has been lea…

Endometriosis may be either symptomatic or asymptomatic. Recurrence rates are mostly calculated on the basis of symptomatic patients re-presenting to their doctor. Based on the number of patients who experience recurrence of symptoms after …

STUDY OBJECTIVE: To study the isolated influence of peritoneal endometrial implants on fertility in an adhesion-free rabbit model. STUDY DESIGN: Thirty-two rabbits with endometrium implants were used; 31 rabbits with fat implants served as…

The reasons for sub-fertility in patients with mild endometriosis remain unclear. Peritoneal fluid constituents may alter tubal transport and embryonic cleavage, with subsequent implantation disturbances. We used an animal model to study th…

In 25 rabbits (Group E) endometrium from the right uterine horn was transplanted onto the peritoneum. In 25 rabbits (Group C) fat was transplanted. After a recovery period of 12 weeks the does were mated, and killed 24 h later. In Group E t…

Endometriosis has an adverse effect on fertility. In severe endometriosis adhesions interfere with ovulation and tubal function. The mechanism by which mild endometriosis causes infertility remains unclear. We studied the effects of endomet…