J.L.H. Evers — Endo Lab

article 2002

Development and characterization of endometriotic lesions in the chick chorioallantoic membrane model

·doi:10.1016/s0015-0282(01)03021-7

article 2001

Development of endometriosis-like lesions after transplantation of human endometrial fragments onto the chick embryo chorioallantoic membrane

Human Reproduction ·doi:10.1093/humrep/16.4.627

The chick embryo chorioallantoic membrane (CAM) bioassay was used to investigate the early pathogenesis of endometriosis. Endometrial fragments were explanted onto the CAM. The grafts including the surrounding CAM were excised at 24, 48 or …

review 2001

The Mesothelium, Teflon or Velcro? Mesothelium in endometriosis pathogenesis

Human Reproduction ·doi:10.1093/humrep/16.4.605

Sampson's transplantation theory for the pathogenesis of peritoneal endometriosis is widely accepted. The events that take place, however, on the cellular and subcellular level during the transition of endometrial tissue in the abdominal ca…

other 2000

Adhesion of menstrual endometrium to extracellular matrix: the possible role of integrin alpha(6)beta(1) and laminin interaction

Molecular human reproduction ·doi:10.1093/molehr/6.2.170

Previous in-vitro studies have shown that the endometrium preferentially adheres to the extracellular matrix (ECM) of the amnion and peritoneum. This interaction probably involves adhesion molecules, e.g. integrins. We evaluated the express…

article 2000

Endometrial Angiogenesis Throughout the Human Menstrual Cycle

·doi:10.1016/s0015-0282(00)01103-1

article 2000

Endometriosis: the enigma persists

·doi:10.1054/ebog.2000.0148

article 2000

Medroxyprogesterone improved symptoms of endometriosis in infertile women

·doi:10.1054/ebog.2000.0194

article 2000

Morphological changes in mesothelial cells induced by shed menstrual endometrium in vitro are not primarily due to apoptosis or necrosis

Human Reproduction ·doi:10.1093/humrep/15.7.1462

In a previous study on the pathogenesis of endometriosis, we observed that constituents of menstrual effluent induce morphological alterations in human mesothelial cells. In this study, we investigated whether these alterations were associa…

article 1999

Adhesion of human endometrial fragments to peritoneum in vitro

·doi:10.1016/s0015-0282(99)00122-3

ObjectiveTo evaluate the adhesion of endometrial fragments obtained during the proliferative phase of the menstrual cycle to fresh human peritoneum obtained during abdominal surgery.DesignA prospective, descriptive, morphologic and cell bio…

article 1999

P-180. Adhesion of menstrual endometrium to extracellular matrix mediated by integrin α6βi and laminin interaction: new insights in the pathogenesis of endometriosis

·doi:10.1093/humrep/14.suppl_3.230-a

Abstracts of the 15th Annual Meeting of the ESHRE, Tours, France 1999 graphy (HSG), an examination which is essential in the routine evaluation of infertile couples, is considered painful. Hysterosonosalpingography (HSS) is a new method for…

article 1998

Adhesion of human endometrium to the epithelial lining and extracellular matrix of amnion in vitro: an electron microscopic study

Human Reproduction ·doi:10.1093/humrep/13.8.2275

One of the first steps in the pathogenesis of endometriosis is the attachment of the endometrium to the peritoneal lining. Since the peritoneum is extremely fragile and hard to obtain, amnion has been used as an in-vitro model to study adhe…

other 1998

"The Flemish Giant", reflections on the defense against endometriosis, inspired by Professor Emeritus Ivo A. Brosens

European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/s0301-2115(98)00199-7

Reproductive research benefits from combining animal and clinical studies. In Leuven, rabbits have constituted an animal model for many reproductive disorders, especially for those that involved surgical treatment. Much of what has been lea…

other 1997

Evaluation of a menstrual cup to collect shed endometrium for in vitro studies

Fertility and sterility ·doi:10.1016/s0015-0282(97)00250-1

OBJECTIVE: To evaluate whether a menstrual cup is a suitable instrument to collect antegradely shed endometrium for in vitro studies. DESIGN: A prospective, descriptive, cell biological and immunohistochemical study. SETTING: Tertiary car…

article 1997

Velocity of endometrial wavelike activity in spontaneous cycles

·doi:10.1016/s0015-0282(97)81478-1

ObjectiveTo analyze the velocity and wave intervals of endometrial wavelike activity in spontaneous menstrual cycles.DesignProspective observational ultrasound (US) evaluation of endometrial wavelike activity.SettingUniversity hospital.Main…

article 1996

Endometrial cell adhesion in an in vitro model using intact amniotic membranes

·doi:10.1016/s0015-0282(16)58030-3

ObjectiveTo study adhesion between endometrial tissue and peritoneum using intact amniotic membranes as an in vitro model.DesignA cell biologic and immunohistochemical study.SettingTertiary-care university medical center.PatientsTen patient…

article 1996

Pathogenesis of endometriosis: Current concepts and new ideas

·doi:10.3109/09513599609116218

other 1996

The defense against endometriosis

Fertility and sterility ·doi:10.1016/s0015-0282(16)58499-4

article 1995

Epithelial cells in peritoneal fluid—of endometrial origin?

American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(95)90283-x

ObjectiveOur purpose was to examine the immunohistochemical properties of epithelial cells in peritoneal fluid and to compare the staining characteristics with cells of endometrium, menstrual effluent, peritoneum, and endometriotic lesions.…

other 1995

Expression of cadherins and integrins in human endometrium throughout the menstrual cycle

Fertility and sterility ·doi:10.1016/s0015-0282(16)57599-2

OBJECTIVE: To detect cadherin and integrin expression in biopsies of endometrium in the phases of the cycle. Cell adhesion molecules may be involved in endometrial shedding during menstruation and attachment of shed endometrial tissue to th…

other 1994

Development of a model of retrograde menstruation in baboons (Papio anubis)

Fertility and sterility ·doi:10.1016/s0015-0282(16)56957-x

article 1994

Expression of integrins E-cadherin in cells from menstrual effluent, endometrium, peritoneal fluid, peritoneum, endometriosis

Fertility and sterility ·doi:10.1016/s0015-0282(16)56457-7

ObjectiveTo detect the expression of integrins and E-cadherin in cells from peritoneal fluid (PF), endometrium, menstrual effluent, peritoneum, and endometriotic lesions during the early follicular phase of the menstrual cycle.DesignAn immu…

review 1994

Is mild endometriosis a disease:Endometriosis does not exist; all women have endometriosis

Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a138421

Journal Article Is mild endometriosis a disease:Endometriosis does not exist; all women have endometriosis Get access Johannes L.H. Evers Johannes L.H. Evers Department of Obstetrics and Gynaecology, Academisch Ziekenhuis Maastricht and The…

review 1993

4 Markers for endometriosis

Bailliere's clinical obstetrics and gynaecology ·doi:10.1016/s0950-3552(05)80460-2

Screening for endometriosis is subject to general rules. The two most important conditions, i.e. the disorder should be well-defined and serious, and there must be an effective way to treat or prevent it through screening, are not satisfied…

article 1993

Early endometriosis invades the extracellular matrix

Fertility and sterility ·doi:10.1016/0020-7292(93)90482-c

OBJECTIVES: To investigate whether the aminoterminal propeptides of type III procollagen are increased in patients with early endometriosis and to demonstrate that the subtle lesion of endometriosis is an active stage of the disease. DESIGN…

review 1993

The luteinized unruptured follicle syndrome

Bailliere's clinical obstetrics and gynaecology ·doi:10.1016/s0950-3552(05)80136-1