Takebayashi K

No ORCID on file · 6 papers in corpus · active 2007-2020

Study types

  • article 6

Condition tags

  • endometriosis 6
  • adenomyosis 1
article 2020
Chemokine expression profiles of ovarian endometriotic stromal cells in three-dimensional culture
Journal of reproductive immunology ·doi:10.1016/j.jri.2020.103100

Endometriosis is a chronic inflammatory disease which is associated with aberrant chemokine expression. We have established a three-dimensional (3D) floating collagen gel culture of human endometriotic cyst stromal cells (ECSCs) as an in vi…

article 2020
hsa-miR-100-5p, an overexpressed miRNA in human ovarian endometriotic stromal cells, promotes invasion through attenuation of SMARCD1 expression
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-020-00590-3

BACKGROUND: A number of microRNAs are aberrantly expressed in endometriosis and are involved in its pathogenesis. Our previous study demonstrated that has-miR-100-5p expression is enhanced in human endometriotic cyst stromal cells (ECSCs). …

article 2019
ATM expression is attenuated by promoter hypermethylation in human ovarian endometriotic stromal cells
Molecular human reproduction ·doi:10.1093/molehr/gaz016

A number of genes involved in the pathogenesis of endometriosis are silenced by the hypermethylation of their promoter regions. We assessed the effect and mechanism of the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-dC) (10 μM) on…

article 2017
Arcyriaflavin a, a cyclin D1–cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-017-0272-3

BACKGROUND: We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to evaluate the potentia…

article 2016
miR-503, a microRNA epigenetically repressed in endometriosis, induces apoptosis and cell-cycle arrest and inhibits cell proliferation, angiogenesis, and contractility of human ovarian endometriotic stromal cells
Human Reproduction ·doi:10.1093/humrep/dew217

STUDY QUESTION: Is the micro-RNA (miRNA) miR-503, downregulated in endometriotic cyst stromal cells (ECSCs) and does this affect the cell cycle, cell proliferation, angiogenesis and contractility of these cells? SUMMARY ANSWER: miR-503 expr…

article 2007
Concomitant treatment of severe uterine adenomyosis in a premenopausal woman with an aromatase inhibitor and a gonadotropin-releasing hormone agonist
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.09.010

ObjectiveTo assess the effect of aromatase inhibitors with GnRH agonist for a severe symptomatic adenomyosis that is refractory to GnRH agonist and danazol with GnRH agonist.DesignCase report.SettingClinical practice in university hospital.…