Li Wu

No ORCID on file · 6 papers in corpus · active 2013-2025

Study types

  • article 1
  • book-chapter 1
  • other 1

Condition tags

  • adenomyosis 2
article 2025
Decoding adenomyosis pathogenesis using an assembloid model
Science China. Life sciences ·doi:10.1007/s11427-025-2981-1

Adenomyosis remains a challenging gynecological disorder to investigate due to the absence of in vitro models that accurately replicate endometrial tissue dynamics across the menstrual cycle. To address this gap, we established an endometri…

other 2024
Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics
Protein & cell ·doi:10.1093/procel/pwae012

Adenomyosis is a poorly understood gynecological disorder lacking effective treatments. Controversy persists regarding "invagination" and "metaplasia" theories. The endometrial-myometrial junction (EMJ) connects the endometrium and myometri…

2023
Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency.
Journal of ovarian research ·doi:10.1186/s13048-023-01266-3

BackgroundPremature ovarian insufficiency (POI) is an important cause of infertility characterized by the functional decline of the ovary. Granulosa cells (GCs) around oocytes are critical for folliculogenesis, and GC dysfunction is one of …

2022
Anticardiolipin and/or anti-β2-glycoprotein-I antibodies are associated with adverse IVF outcomes.
Frontiers in immunology ·doi:10.3389/fimmu.2022.986893

ObjectiveThe purpose of the study is to evaluate the effects of anticardiolipin (aCL) and/or anti-β2-glycoprotein-I (aβ2GPI) antibodies, namely antiphospholipid antibodies (aPL), on in vitro fertilization (IVF) outcomes.Materials and method…

book-chapter 2022
The ovarian immune pathology and reproductive failures
·doi:10.1016/b978-0-323-90805-4.00018-3
2013
A retrospective study on IVF/ICSI outcome in patients with anti-nuclear antibodies: the effects of prednisone plus low-dose aspirin adjuvant treatment.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-11-98

BackgroundAnti-nuclear antibodies (ANA) are suspected of having relevance to adverse reproductive events.MethodsThis study aims to investigate the potential effect of ANA on IVF/ICSI outcome and the therapeutic role of prednisone plus low-d…