Guan R

No ORCID on file · 6 papers in corpus · active 2014-2025

Study types

  • other 1
  • preprint 1

Condition tags

  • infertility 3
  • endometriosis 2
2025
Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01406-y

BackgroundWhile the phenotypic link between body mass index (BMI) and some female reproductive disorders is well established, the genetic architecture and causal relationships have not been systematically studied. We aimed to create an atla…

2025
Exploring the potential benefits of growth hormone co-treatment on embryo quality in IVF: a randomized controlled open-label trial.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01374-3

Research questionWhile growth hormone (GH) is hypothesized to potentially enhance embryo quality, results of current basic and clinical researches remain inconclusive. This study assesses the effect of GH supplementation on embryo quality a…

other 2024
Investigating the metabolomic pathways in female reproductive endocrine disorders: a Mendelian randomization study
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1438079

INTRODUCTION: Reproductive endocrine disorders (RED), including polycystic ovary syndrome (PCOS), endometriosis (EMs), and female infertility (FI), significantly affect women's health globally, with varying prevalence across different regio…

preprint 2024
Investigating the Metabolomic Pathways in Female Reproductive Endocrine Disorders: A Mendelian Randomization Study
·doi:10.21203/rs.3.rs-4207495/v1

Abstract Background Reproductive endocrine disorders (RED) including polycystic ovary syndrome (PCOS), endometriosis (EMs), and female infertility (FI), significantly affect women's health globally, with varying prevalence across different …

2023
Comprehensive molecular expression profiling of SARS-CoV-associated factors in the endometrium across the menstrual cycle and elevated susceptibility in women with recurrent pregnancy loss.
Frontiers in genetics ·doi:10.3389/fgene.2023.1246725

Objective: To evaluate the dynamic expression profiling alterations of SARS-CoV-2-associated molecules within the fertile human endometrium throughout the menstrual cycle. Furthermore, to explore the inherent vulnerability of the endometriu…

2014
MiR-133b regulates the expression of the Actin protein TAGLN2 during oocyte growth and maturation: a potential target for infertility therapy.
PloS one ·doi:10.1371/journal.pone.0100751

Infertility is an area of increasing in life science research. Although follicular maturation disorders and anovulation are the primary causations of infertility, its molecular mechanism is not well understood. Recent research has shown tha…