Faubion SS

It is now recognized that there are significant differences between the sexes affecting prevalence, incidence, and severity over a broad range of diseases, although the extent of the differences is not fully elucidated. Until the early 1990…

OBJECTIVE: There is limited information on the prevalence of premature and early menopause. Therefore, we studied the frequency and type of premature (age < 40 years) or early (age 40-44 years) menopause in a geographically-defined American…

ObjectiveTo study the trajectories of metabolic parameters after bilateral oophorectomy.Study designThis population-based cohort study included a random sample of all premenopausal women who underwent bilateral oophorectomy at or before age…

Bilateral oophorectomy in premenopausal women is a unique condition causing the abrupt and premature loss of ovarian hormones, primarily estrogen. Bilateral oophorectomy causes an alteration of several fundamental aging processes at the cel…

ObjectivesWe investigated the association of personal, reproductive, and familial characteristics with bilateral oophorectomy performed for nonmalignant indications in a US population.Study designIn an established cohort study, we used the …

ObjectivesBilateral oophorectomy has commonly been performed in conjunction with hysterectomy even in women without a clear ovarian indication; however, oophorectomy may have long-term deleterious consequences. To better understand this sur…

BackgroundThe cause-effect relationship between bilateral oophorectomy and accelerated aging remains controversial. We conducted new analyses to further address this controversy.MethodsThe Rochester Epidemiology Project records-linkage syst…

PurposeThis cohort study was established to investigate the effects of unilateral and bilateral oophorectomy on the ageing processes in women.ParticipantsWe used the records-linkage system of the Rochester Epidemiology Project (REP, http://…

ObjectiveTo study the association between bilateral oophorectomy and the rate of accumulation of multimorbidity.Patients and methodsIn this historical cohort study, the Rochester Epidemiology Project records-linkage system was used to ident…

Nonrelaxing pelvic floor dysfunction is not widely recognized. Unlike in pelvic floor disorders caused by relaxed muscles (eg, pelvic organ prolapse or urinary incontinence, both of which often are identified readily), women affected by non…