Siby Sebastian

No ORCID on file · 5 papers in corpus · active 2001-2002

Study types

  • article 2
  • review 2
  • other 1

Condition tags

  • mesh:D004715 3
  • endometriosis 3
review 2002
Estrogen Production and Metabolism in Endometriosis
Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2002.tb02767.x

Aromatase activity is absent in normal endometrium. In contrast, aromatase is expressed aberrantly in endometriosis, which gives rise to strikingly high levels of aromatase activity in this tissue. Both aromatase expression and activity are…

review 2002
Mechanisms of excessive estrogen formation in endometriosis
Journal of reproductive immunology ·doi:10.1016/s0165-0378(01)00132-2
article 2002
Wilms’ tumor 1 inhibits aromatase P450 expression in human cells and is downregulated in endometriosis vs. endometrium-derived stromal cells
·doi:10.1016/s0015-0282(02)03385-x
other 2002
WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2002-020522

The orphan nuclear receptor steroidogenic factor-1 (SF-1) induces the expression of Müllerian inhibiting substance (MIS) and many steroidogenic genes, including aromatase P450 (P450arom). Dosage-sensitive sex reversal adrenal hypoplasia con…

article 2001
Transcriptional regulation of the CYP1A1 gene by dioxin in eutopic endometrial and endometriotic stromal cells.
·doi:10.1016/s0015-0282(01)02156-2