Jianfeng Zhou

ORCID: 0000-0002-1332-9230 · 4 papers in corpus
review 2002
Mechanisms of excessive estrogen formation in endometriosis
Journal of Reproductive Immunology ·doi:10.1016/s0165-0378(01)00132-2

Estrogen is produced in a number of human tissues including the ovary, placenta and extraglandular sites such as adipose tissue, skin and the brain. Aromatase is the key enzyme that regulates estrogen formation in these tissues. Aromatase a…

article 2002
Regulation of Aromatase P450 Expression in Endometriotic and Endometrial Stromal Cells by CCAAT/Enhancer Binding Proteins (C/EBPs): Decreased C/EBPβ in Endometriosis Is Associated with Overexpression of Aromatase
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.87.5.8486

In human endometriotic stromal cells, markedly high levels of aromatase P450 (P450arom) mRNA and promoter II activity are present and can be vigorously stimulated by PGE(2) via a cAMP-dependent pathway to give rise to physiologically signif…

other 2002
WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2002-020522

The orphan nuclear receptor steroidogenic factor-1 (SF-1) induces the expression of Müllerian inhibiting substance (MIS) and many steroidogenic genes, including aromatase P450 (P450arom). Dosage-sensitive sex reversal adrenal hypoplasia con…

article 2001
Regulation of aromatase P450 promoter (II) activity in endometriotic stromal cells by CCAAT/enhancer binding proteins (C/EBPs).
·doi:10.1016/s0015-0282(01)02149-5