Wilms’ tumor 1 inhibits aromatase P450 expression in human cells and is downregulated in endometriosis vs. endometrium-derived stromal cells

Bilgin Gürateş, Siby Sebastian, Sijun Yang, Mitsutoshi Tamura, Zong Juan Fang, Serdar E. Bulun
In: Fertility and Sterility · 2002 · vol. 78 , pp. S2–S3 · doi:10.1016/s0015-0282(02)03385-x · W2068127816
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

Wilms’ tumor 1 (WT1) was found to inhibit aromatase P450 expression in human cells, with its levels significantly reduced in endometriosis-derived stromal cells compared to normal endometrium.

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endometriosis

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