Michael Gabriel

No ORCID on file · 7 papers in corpus · active 2018-2025

Study types

  • article 6
  • dataset 1

Condition tags

  • endometriosis 6
  • infertility 2
  • adenomyosis 1
article 2025
Reproductive medicine and biology ·doi:10.1002/rmb2.12645

PURPOSE: Endometriosis is a chronic gynecological disorder associated with pain symptoms and infertility. The expression of microRNA miR-29c-3p is dysregulated in endometriosis. We aimed to identify novel molecular targets of miR-29c-3p fun…

article 2022
International journal of molecular sciences ·doi:10.3390/ijms23052851

The stem cell marker and RNA-binding protein Musashi-1 is overexpressed in endometriosis. Musashi-1-siRNA knockdown in Ishikawa cells altered the expression of stem cell related genes, such as OCT-4. To investigate the role of both human Mu…

article 2022
International journal of molecular sciences ·doi:10.3390/ijms23094815

Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is an enzyme that converts estrone to estradiol, while adenomyosis is an estrogen-dependent disease with poorly understood pathophysiology. In the present study, we show that mice unive…

article 2022
·doi:10.1093/humrep/deac107.302

Abstract Study question Do Musashi proteins mechanistically contribute to the pathogenetic properties of endometriotic cells? Summary answer Silencing of Musashi-1 and Muashi-2 reduces the expression of stemness-related genes, inhibits sphe…

article 2020
Scientific data ·doi:10.1038/s41597-020-00623-x

Endometriosis is a common inflammatory estrogen-dependent gynecological disorder, associated with pelvic pain and reduced fertility in women. Several aspects of this disorder and its cellular and molecular etiology remain unresolved. We hav…

dataset 2020
·doi:10.6084/m9.figshare.12195975

Endometriosis is a common inflammatory estrogen-dependent gynecological disorder, associated with pelvic pain and reduced fertility in women. Several aspects of this disorder and its cellular and molecular etiology remain unresolved. We hav…

article 2018
Human Reproduction ·doi:10.1093/humrep/dey026

STUDY QUESTION: What is the role of SFRP2 in endometriosis? SUMMARY ANSWER: SFRP2 acts as a canonical WNT/CTNNB1 signaling agonist in endometriosis, regulating endometriosis lesion growth and indicating endometriosis lesion borders together…