Garcia R

No ORCID on file · 3 papers in corpus · active 2013-2021

Study types

  • article 1

Condition tags

  • dysmenorrhea 1
  • endometriosis 1
  • chronic_pelvic_pain 1
article 2021
A model‐based analysis to guide gonadotropin‐releasing hormone receptor antagonist use for management of endometriosis
British journal of clinical pharmacology ·doi:10.1111/bcp.15171

AIMS: To identify linzagolix doses, an oral GnRH receptor antagonist, that effectively lower oestradiol (E2) to relieve endometriosis-related pelvic pain without compromising bone health. METHODS: Integrated statistical, pharmacokinetic-pha…

2016
Ovarian Cancer: The Fallopian Tube as the Site of Origin and Opportunities for Prevention.
Frontiers in oncology ·doi:10.3389/fonc.2016.00108

High-grade serous carcinoma (HGSC) is the most common and aggressive histotype of epithelial ovarian cancer (EOC), and it is the predominant histotype associated with hereditary breast and ovarian cancer syndrome (HBOC). Mutations in BRCA1 …

2013
The baboon kidney transcriptome: analysis of transcript sequence, splice variants, and abundance.
PloS one ·doi:10.1371/journal.pone.0057563

The baboon is an invaluable model for the study of human health and disease, including many complex diseases of the kidney. Although scientists have made great progress in developing this animal as a model for numerous areas of biomedical r…